Evidence map›Paper›PMID 42041743›Full record

Trial reportCurrent oncology (Toronto, Ont.)2026

A Randomized Trial Evaluating Personalized Versus Guideline-Based Well Follow-Up Strategies for Patients with Early Breast Cancer: Feasibility Outcomes.

Ana-Alicia Beltran-Bless, Emma Himmelman, Alexander Kim, Gregory R Pond, Parvaneh Fallah, Terry Ng, John Hilton, Marie-France Savard, Gail Larocque, Kelly-Anne Baines and 5 more

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Current oncology (Toronto, Ont.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05365230 (A Randomized Trial Evaluating Personalized vs Guideline-based Well Follow-up Strategies for Patients With Early-stage Breast Cancer), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05365230 phase4completednot on this map

A Randomized Trial Evaluating Personalized vs Guideline-based Well Follow-up Strategies for Patients With Early-stage Breast Cancer (REaCT-Wellness)

TypeinterventionalSponsorOttawa Hospital Research InstituteRan2022 to 2025Enrolled261ConditionsBreast CancerArmsOn-demand personalized follow-up care, Guideline-based follow-up care (standard of care)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ana-Alicia Beltran-BlessDepartment of Medicine, Division of Medical Oncology, The Ottawa Hospital and University of Ottawa, 501 Smyth Road, Ottawa, ON K1H 8L6, Canada.ORCID 0000-0003-4880-8167
Emma HimmelmanCancer Therapeutics Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
Alexander KimCancer Therapeutics Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
Gregory R PondEscarpment Cancer Research Institute, McMaster University, Hamilton, ON L8V 1C3, Canada.ORCID 0000-0003-1033-0882
Parvaneh FallahDepartment of Medicine, Division of Medical Oncology, The Ottawa Hospital and University of Ottawa, 501 Smyth Road, Ottawa, ON K1H 8L6, Canada.ORCID 0000-0001-7885-2009
Terry NgDepartment of Medicine, Division of Medical Oncology, The Ottawa Hospital and University of Ottawa, 501 Smyth Road, Ottawa, ON K1H 8L6, Canada.ORCID 0000-0001-6128-3137
John HiltonDepartment of Medicine, Division of Medical Oncology, The Ottawa Hospital and University of Ottawa, 501 Smyth Road, Ottawa, ON K1H 8L6, Canada.ORCID 0000-0002-6280-8633
Marie-France SavardDepartment of Medicine, Division of Medical Oncology, The Ottawa Hospital and University of Ottawa, 501 Smyth Road, Ottawa, ON K1H 8L6, Canada.ORCID 0000-0002-7651-0870
Gail LarocqueOttawa Hospital Cancer Centre, The Ottawa Hospital, Ottawa, ON K1H 1C4, Canada.ORCID 0000-0001-9979-6659
Kelly-Anne BainesOttawa Hospital Cancer Centre, The Ottawa Hospital, Ottawa, ON K1H 1C4, Canada.
Kendra PrimeauOttawa Hospital Cancer Centre, The Ottawa Hospital, Ottawa, ON K1H 1C4, Canada.
Deanna SaundersCancer Therapeutics Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.ORCID 0009-0000-8403-0343
Danielle AllardCancer Therapeutics Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.ORCID 0009-0008-6295-122X
Lisa VandermeerCancer Therapeutics Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.ORCID 0000-0001-5921-1441
Mark ClemonsDepartment of Medicine, Division of Medical Oncology, The Ottawa Hospital and University of Ottawa, 501 Smyth Road, Ottawa, ON K1H 8L6, Canada.ORCID 0000-0001-9392-8219

Funding

The Ottawa Hospital Academic Medical Organization TOH 22-001
6 · The paper itself

Abstract

Despite the paucity of high-quality data supporting its benefits, routinely scheduled, in-person post-treatment surveillance of early breast cancer (EBC) patients remains common. Evaluation of different follow-up strategies is required. We present the feasibility phase of an ongoing randomized controlled trial (RCT) comparing two different follow-up strategies. Patients with EBC who completed the acute phase of their treatment were randomized to receive either personalized or ASCO guideline-based follow-up care alone. Feasibility endpoints, including rate of accrual, physician participation, patient acceptance of randomization arm, and patient retention 1 year after randomization, are presented. Of 279 patients approached, 261 (93.5%) were eligible and provided consent. Median rate of accrual was 34.5 patients per month, and all healthcare providers who agreed to study participation (

Indexed as

Breast NeoplasmsPrecision MedicineAdultAgedFeasibility StudiesFemaleFollow-Up StudiesHumansMiddle AgedPractice Guidelines as Topicbreast cancerfollow-uppost-treatmentsurveillance

Identifiers

PMID42041743
PMCPMC13114694

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.