Evidence map›Paper›PMID 42041609›Full record

ReviewDiseases (Basel, Switzerland)2026

Critical Care Sedation: Emerging Clinical Considerations and Risks of Volatile Anesthetics for Sedation: A Narrative Review.

Austin M Breaux, Garret R Miller, Harrison D Cooper, Kristin Nicole Bembenick, Aishwarya Reddy, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D Kaye

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Diseases (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Austin M BreauxSchool of Medicine, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA 71103, USA.
Garret R MillerSchool of Medicine, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA 71103, USA.
Harrison D CooperSchool of Medicine, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA 71103, USA.ORCID 0009-0000-6995-891X
Kristin Nicole BembenickDepartment of Anesthesiology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA 71103, USA.
Aishwarya ReddyDepartment of Anesthesiology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA 71103, USA.
Shahab AhmadzadehDepartment of Anesthesiology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA 71103, USA.
Sahar ShekoohiDepartment of Anesthesiology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA 71103, USA.ORCID 0009-0007-4545-4523
Alan D KayeDepartment of Anesthesiology, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA 71103, USA.ORCID 0000-0003-2464-0187

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Volatile anesthetics have steadily become more popular in intensive care units for sedation for reasons related to their beneficial pharmacokinetic and pharmacodynamic properties. Common anesthetics such as isoflurane and sevoflurane rapidly reach sedative levels in the body, but they are also rapidly eliminated, allowing for quick recovery. These agents have minimal impact on the liver and kidneys, which makes them attractive options when compared to other agents including opioids, benzodiazepines, ketamine, and propofol. Use of delivery systems like AnaConDa

Indexed as

anxiolysisintensive care unitsisofluranepropofolsedationsevofluranevolatile anesthetics

Identifiers

PMID42041609
PMCPMC13114270

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.