Evidence map›Paper›PMID 42041523›Full record

ArticleCells2026

From Phage Display to Yeast Secretion: Developing Fc-Fused Nanobodies Against Influenza Virus.

Mei Wang, Shujun Li, Yong Li, Xiaomei Xia, Yan Zhang, Ning Cao, Yuanfang Li, Yijia Liu, Sheng Zhang, Lilin Zhang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mei WangSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Shujun LiSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Yong LiSchool of Life Sciences, Tianjin University, Tianjin 300072, China.ORCID 0009-0004-8238-6708
Xiaomei XiaSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Yan ZhangSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Ning CaoSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Yuanfang LiSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Yijia LiuSchool of Life Sciences, Tianjin University, Tianjin 300072, China.
Sheng ZhangTianjin Zoo, Tianjin 300070, China.
Lilin ZhangSchool of Life Sciences, Tianjin University, Tianjin 300072, China.ORCID 0000-0001-5642-0379
Jinhai HuangSchool of Life Sciences, Tianjin University, Tianjin 300072, China.ORCID 0000-0002-1073-533X

Funding

Shandong Key Science and Technology Project 2025TSGCCZZB015Tianjin Municipal Major Science and Technology Projects and Engineering 25ZXCKQY00020Tianjin Natural Science Foundation Project 24YFZCSN00180
6 · The paper itself

Abstract

Avian influenza infections cause substantial economic losses in the poultry industry and raise public health concerns due to viral adaptation and cross-species transmission. The frequent antigenic drift of influenza viruses further complicates the prevention and treatment of avian respiratory infections. In this study, we generated high-affinity heavy-chain variable domain (VHH) nanobodies from naïve alpaca/camelid VHH libraries using phage display combined with H9N2

Indexed as

Cell Surface Display TechniquesImmunoglobulin Fc FragmentsInfluenza A virusSaccharomyces cerevisiaeSingle-Domain AntibodiesAnimalsCamelids, New WorldDogsInfluenza A Virus, H9N2 SubtypeMadin Darby Canine Kidney CellsMolecular Docking SimulationNeuraminidasePeptide LibraryImmunoglobulin Fc FragmentsNeuraminidasePeptide LibrarySingle-Domain AntibodieshemagglutininIgY Fc fusioninfluenzananobodyneuraminidasephage displaySaccharomyces cerevisiaeVHHVHH-Fc fusion

Identifiers

PMID42041523
PMCPMC13114647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.