Evidence map›Paper›PMID 42041417›Full record

ArticleBiosensors2026

A Programmable and Portable Electromagnetic Microfluidic Platform for Droplet Manipulation.

Chaoze Xue, Shilun Feng, Wenshuai Wu, Zhe Zhang, Jianlong Zhao, Gaozhe Cai, Ting Zhou

Abstract read
In one paragraph

Article in Biosensors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chaoze XueSchool of Microelectronics, Shanghai University, Shanghai 201899, China.
Shilun FengState Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 201899, China.ORCID 0000-0002-2560-2417
Wenshuai WuKey Laboratory of Environmental Medicine and Engineering, Ministry of Education, Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing 210009, China.
Zhe ZhangSchool of Microelectronics, Shanghai University, Shanghai 201899, China.
Jianlong ZhaoSchool of Microelectronics, Shanghai University, Shanghai 201899, China.
Gaozhe CaiSchool of Microelectronics, Shanghai University, Shanghai 201899, China.
Ting ZhouSchool of Microelectronics, Shanghai University, Shanghai 201899, China.ORCID 0000-0002-0420-0566

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Droplet manipulation constitutes a fundamental operation in numerous bio-microfluidic applications, including but not limited to medical diagnostics and targeted drug delivery. Among the various technologies developed for this purpose, magnetic digital microfluidics (MDMF) has emerged as a compelling approach due to its inherent advantages of contamination-free actuation, low cost, and configurational flexibility. Nevertheless, conventional MDMF remains constrained by its reliance on bulky instrumentation and substantial power consumption for generating controllable magnetic fields, which limit its in-field applications. To address these limitations, this work presents a programmable and portable electromagnetic microfluidic droplet manipulation platform that synergistically integrates static and dynamic magnetic fields to enable non-contact, high-precision droplet control under ultra-low power conditions. The proposed system comprises an electromagnetic actuation module, a permanent magnet, and a glass substrate coated with Teflon film. The entire system is secured by a PMMA support structure, within which a glass substrate is mounted and spatially separated from the permanent magnet. The PMMA support is fabricated using a milling process, offering a simple manufacturing procedure and high structural reusability and reproducibility. The control logic is implemented on a field-programmable gate array (FPGA) development board, facilitating fully autonomous operation powered by a standard battery. The platform operates at a low voltage of 3.5 V and a driving current of 180 mA, corresponding to a total power consumption of merely 0.63 W, while achieving robust manipulation of droplets in the volume range of 0.5 to 5 μL. A maximum average droplet velocity of up to 0.6 cm/s was attained under optimal conditions. The proposed platform offers a scalable and energy-efficient solution for portable droplet-based assays and holds significant promise for integration into point-of-care diagnostic tools and field-ready biochemical analysis systems. The platform demonstrates excellent operational stability and reproducibility, as validated by repeated actuation experiments with a positioning deviation of approximately 0.1 mm under optimized conditions. The fabrication process also exhibits high reliability with consistent performance across multiple experimental runs.

Indexed as

Biosensing TechniquesMicrofluidic Analytical TechniquesMicrofluidicsEquipment Designdroplet manipulationelectromagnetic control systemmagnetic digital microfluidicsportableprogrammable

Identifiers

PMID42041417
PMCPMC13114064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.