Evidence map›Paper›PMID 42041415›Full record

ArticleBiosensors2026

Fluorescence Immunosensor with Phage Antibodies for Heat Shock Protein 70 Detection.

Olga I Guliy, Sergei A Eremin, Liliya I Mukhametova, Evgeniy S Kozlov, Vyacheslav S Grinev, Sergey A Staroverov, Olga A Karavaeva, Ksenia K Fursova, Fedor A Brovko, Lev A Dykman and 1 more

Abstract read
In one paragraph

Article in Biosensors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Olga I GuliyInstitute of Biochemistry and Physiology of Plants and Microorganisms-Subdivision of the Federal State Budgetary Research Institution Saratov Federal Scientific Centre of the Russian Academy of Sciences (IBPPM RAS), Saratov 410049, Russia.ORCID 0000-0002-0541-0020
Sergei A EreminDepartment of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia.
Liliya I MukhametovaDepartment of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia.ORCID 0000-0002-5896-2523
Evgeniy S KozlovDepartment of Animal Diseases and Veterinary-Sanitary Expertise, Institute of Veterinary Medicine and Pharmacy, Vavilov Saratov State University of Genetics, Biotechnology and Engineering, Saratov 410012, Russia.
Vyacheslav S GrinevInstitute of Biochemistry and Physiology of Plants and Microorganisms-Subdivision of the Federal State Budgetary Research Institution Saratov Federal Scientific Centre of the Russian Academy of Sciences (IBPPM RAS), Saratov 410049, Russia.ORCID 0000-0002-0627-6804
Sergey A StaroverovInstitute of Biochemistry and Physiology of Plants and Microorganisms-Subdivision of the Federal State Budgetary Research Institution Saratov Federal Scientific Centre of the Russian Academy of Sciences (IBPPM RAS), Saratov 410049, Russia.
Olga A KaravaevaInstitute of Biochemistry and Physiology of Plants and Microorganisms-Subdivision of the Federal State Budgetary Research Institution Saratov Federal Scientific Centre of the Russian Academy of Sciences (IBPPM RAS), Saratov 410049, Russia.ORCID 0000-0002-0665-1846
Ksenia K FursovaBranch of Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Pushchino 142290, Russia.
Fedor A BrovkoBranch of Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Pushchino 142290, Russia.
Lev A DykmanInstitute of Biochemistry and Physiology of Plants and Microorganisms-Subdivision of the Federal State Budgetary Research Institution Saratov Federal Scientific Centre of the Russian Academy of Sciences (IBPPM RAS), Saratov 410049, Russia.ORCID 0000-0003-2440-6761
Qingyun LiuCollege of Chemical and Biological Engineering, Shandong University of Science and Technology, Qingdao 266590, China.

Funding

Russian Science Foundation 25-44-02132
6 · The paper itself

Abstract

The detection of biological markers is critical not only for the early diagnosis of cancer but also for adjustments in antitumor therapy. Rapid, sensitive, and selective detection and monitoring of the content of specific biomarkers in real time are key to point-of-care testing diagnostics. We report the detection of heat shock proteins by fluorescence immunoassay with the appropriate phage antibodies, with a minimum detection limit of 1 ng/mL. The fluorescence immunoassay data were confirmed by dot immunoassay and by circular dichroism studies. The results of the study may help in the adaptation of the fluorescence immunoassay to cancer diagnostics.

Indexed as

Biosensing TechniquesHSP70 Heat-Shock ProteinsCircular DichroismFluorescenceHumansImmunoassayHSP70 Heat-Shock Proteinscancer markerscircular dichroismdot immunoassayfluorescence immunoassayheat shock proteinsphage antibodies

Identifiers

PMID42041415
PMCPMC13115360

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.