Evidence map›Paper›PMID 42041308›Full record

ArticleAntibiotics (Basel, Switzerland)2026

Drug-Resistant Gram-Positive Cocci as Etiological Factors of Cardiac Implantable Electronic Device Infections-Data from the EXTRACT Registry.

Danuta Łoboda, Sylwia Gładysz-Wańha, Michał Joniec, Eugeniusz Piłat, Robert D Wojtyczka, Beata Sarecka-Hujar, Julia Staroń, Denis Swolana, Michał Gibiński, Karolina Simionescu and 2 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05775783 (Effectiveness, Complications, and Mortality of Transvenous Lead Extraction in Patients With and Without Infections-Prospective Registry From a High-volume Center.), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05775783 completednot on this map

Effectiveness, Complications, and Mortality of Transvenous Lead Extraction in Patients With and Without Infections-Prospective Registry From a High-volume Center.

Typeobservational_patient_registrySponsorMedical University of SilesiaRan2016 to 2025Enrolled702ConditionsTransvenous Lead ExtractionArmsTransvenous lead extraction
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Danuta ŁobodaDepartment of Electrocardiology and Heart Failure, Medical University of Silesia, 40-635 Katowice, Poland.ORCID 0000-0003-2932-6269
Sylwia Gładysz-WańhaDepartment of Electrocardiology, Upper-Silesian Medical Centre in Katowice, 40-635 Katowice, Poland.ORCID 0000-0002-8770-8321
Michał JoniecDepartment of Electrocardiology, Upper-Silesian Medical Centre in Katowice, 40-635 Katowice, Poland.ORCID 0000-0003-0562-9695
Eugeniusz PiłatDepartment of Electrocardiology, Upper-Silesian Medical Centre in Katowice, 40-635 Katowice, Poland.
Robert D WojtyczkaDepartment of Microbiology, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, 41-200 Sosnowiec, Poland.ORCID 0000-0002-0334-0938
Beata Sarecka-HujarDepartment of Basic Biomedical Science, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, 41-200 Sosnowiec, Poland.ORCID 0000-0003-0002-8591
Julia StarońDepartment of Electrocardiology, Upper-Silesian Medical Centre in Katowice, 40-635 Katowice, Poland.
Denis SwolanaDepartment of Microbiology, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, 41-200 Sosnowiec, Poland.ORCID 0000-0002-5508-7567
Michał GibińskiDepartment of Electrocardiology and Heart Failure, Medical University of Silesia, 40-635 Katowice, Poland.
Karolina SimionescuDepartment of Electrocardiology and Heart Failure, Medical University of Silesia, 40-635 Katowice, Poland.
Sławomir WilczyńskiDepartment of Basic Biomedical Science, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, 41-200 Sosnowiec, Poland.ORCID 0000-0002-6066-3127
Krzysztof S GołbaDepartment of Electrocardiology and Heart Failure, Medical University of Silesia, 40-635 Katowice, Poland.ORCID 0000-0001-5722-7976

Funding

Medical University of Silesia in Katowice and the Medical Research Agency as part of the National Recovery and Resilience Plan 2024/ABM/03/KPO/KPOD.07.07-IW.07-0004/24-00
6 · The paper itself

Abstract

introductionBacterial multidrug resistance (MDR) drives treatment with expensive, toxic, or pharmacokinetically suboptimal antibiotics.

objectivesTo assess the prevalence of MDR Gram-positive cocci among isolates from cardiac implantable electronic device (CIED) infections at a Polish reference center.

methodsData come from the "EXTRACT" registry (ClinicalTrials.gov ID NCT05775783), which covers 702 transvenous lead extraction procedures. Blood samples and intraoperative swabs were collected from participants with CIED infection.

resultsFrom 209 cases with isolated pocket infection (PI) (107, 51.2%) or systemic infections (102, 48.8%), 263 Gram-positive cocci were cultured. They were: coagulase-negative staphylococci (CoNS) (177, 67.3%),

conclusionsEpidemiological data may improve the effectiveness of empirical antibiotic therapy for CIED-related infections.

Indexed as

antimicrobial resistancecardiac implantable electronic deviceGram-positive cocciinfective endocarditismultidrug resistancepocket erosionpocket infectiontransvenous lead extraction

Identifiers

PMID42041308
PMCPMC13113275

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.