Combinatorial Design of Slippery, Nitric Oxide-Releasing Surfaces Incorporating Copper Nanoparticles for Blood-Contacting Devices.

Vicente D Pinon, Mark Garren, Yi Wu, Grace H Nguyen, Elizabeth J Brisbois, Hitesh Handa

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Article in ACS applied materials & interfaces, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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5 · Who and what money

Authors and funding

6 authors.

Vicente D PinonDepartment of Pharmaceutical & Biomedical Sciences, University of Georgia, Athens, Georgia 30602, United States.

Mark GarrenSchool of Chemical, Materials, and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia 30602, United States.ORCID 0000-0001-5194-6558

Yi WuSchool of Chemical, Materials, and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia 30602, United States.

Grace H NguyenSchool of Chemical, Materials, and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia 30602, United States.ORCID 0009-0009-2939-8394

Elizabeth J BrisboisSchool of Chemical, Materials, and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia 30602, United States.ORCID 0000-0002-9283-5448

Hitesh HandaDepartment of Pharmaceutical & Biomedical Sciences, University of Georgia, Athens, Georgia 30602, United States.ORCID 0000-0002-9369-7374

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hospital acquired infections (HAIs) remain a prevailing issue in clinical settings. These challenges are associated with the health and economic burdens of complications such as bloodstream infections, biomedical device fouling, and antimicrobial resistance. Nitric oxide (NO) is an endogenous gasotransmitter that has vasodilatory, antimicrobial, and antiplatelet effects. This has allowed NO to surface as a potential bioactive strategy for integration into medical device technologies. When combined with other surface modifications, such as liquid infusion (LI) and copper nanoparticles(CuNPs), this approach yields slippery, antifouling surfaces with dual antibacterial and NO-catalysis properties. Herein, we combined

Indexed as

Anti-Bacterial AgentsCopperMetal NanoparticlesNitric OxideNitric Oxide DonorsEscherichia coliHumansMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsS-Nitroso-N-AcetylpenicillamineSurface PropertiesAnti-Bacterial AgentsCopperNitric OxideNitric Oxide DonorsS-Nitroso-N-Acetylpenicillamineantibacterialcopper nanoparticlesliquid infusionnitric oxide

Identifiers

PMID42041124

DOI10.1021/acsami.6c02385

PMCPMC13154129

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