Evidence map›Paper›PMID 42041078›Full record

ArticleJournal of biological rhythms2026

A Lentiviral Fluorescent Reporter to Study Circadian Rhythms in Single Cells.

Christian H Gabriel, Luis Lehmann, Joana Ahlburg, Achim Kramer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biological rhythms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christian H GabrielDivision of Chronobiology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0000-0003-2081-1743
Luis LehmannDivision of Chronobiology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Joana AhlburgDivision of Chronobiology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0009-0000-6877-8642
Achim KramerDivision of Chronobiology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.ORCID 0000-0001-9671-6078

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circadian rhythms-self-sustained, ~24-h oscillations in transcript and protein levels-are generated by a cell-autonomous molecular clock. These rhythms shape how individual cells respond to external signals, influencing key decisions such as differentiation and apoptosis. However, current tools for visualizing circadian rhythms at the single-cell level often rely on genomic engineering and clonal expansion, limiting their accessibility and applicability. We present fluorescent circadian reporters based on the murine

Indexed as

Circadian RhythmGenes, ReporterLentivirusSingle-Cell AnalysisAnimalsCircadian ClocksHumansMiceNuclear Receptor Subfamily 1, Group D, Member 1Time-Lapse ImagingNuclear Receptor Subfamily 1, Group D, Member 1circadian rhythmsfluorescent reporterlentiviral transductionlive-cell microscopyREVERBαsingle-cell imaging

Identifiers

PMID42041078
PMCPMC13342504

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.