Surgical Treatment Options and the Subtypes of Cesarean Scar Pregnancy Did Not Affect the Probability of a Subsequent Pregnancy: A Prospective Cohort Study.

Background and Aim: Cesarean scar pregnancy (CSP) is rare but poses a potentially life-threatening complication. There is currently insufficient evidence in the literature regarding the impact of CSP treatment on future fertility due to limited clinical studies on a large scale. Here, we investigated the future reproductive outcomes of women with CSP. Methods: From December 2019 to July 2023, women diagnosed with CSP at the Hospital of Obstetrics and Gynaecology of Fudan University, Shanghai, China, were followed up by telephone calls. Data on future fertility and outcomes were collected. Results: Among 302 women, excluding three who did not answer the question, 234 (77.5%) did not express their intention to conceive in future, while only 65 (22%) expressed an intention to conceive again. Among these 65 women intending to conceive, 14 (21.5%) achieved pregnancy. In contrast, among women who did not intend to conceive, 31 (15.4%) achieved pregnancy. After excluding women within 12 months of treatment, the analysis showed no statistical difference in successful conception between women who intended to conceive again and those who did not ( Conclusion: Our study found that 22% of women with CSP intended to conceive, and 29% of our study cohort had a subsequent pregnancy. There was no association between treatment options or CSP subtype and successful conception. Additionally, the incidence of complications in subsequent pregnancies was comparable to that reported in the literature for women without a history of CSP. Our findings suggest that surgical treatments for CSP may not negatively affect future fertility.