ArticleCase reports in oncology
Importance of Cerebrospinal Fluid Flow Cytometry in Pediatric Acute Lymphoblastic Leukemia.
Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Acute lymphoblastic leukemia (ALL) is the most common malignancy in children. Central nervous system (CNS) leukemia is usually diagnosed using microscopy and cytospin-based cytology, which has low sensitivity for detecting minimal events. Following the evaluation of bone marrow aspiration samples using flow cytometry (FC), it has been found to be valuable in the risk group stratification and follow-up of ALL. Recently, there have been discussions regarding the routine use of cerebrospinal fluid (CSF) FC analysis for CNS leukemia at diagnosis and/or relapse in ALL protocols. Case Presentation: We present a case of ALL in which the CSF cytospin-based cytology analysis revealed no blasts, whereas the FC analysis of the CSF showed 1.6% blasts during the maintenance therapy. The patient developed an overt CNS relapse within 3 months. Conclusion: We would like to emphasize the importance of using more sensitive techniques to evaluate CNS involvement in patients with ALL.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.