Evidence map›Paper›PMID 42040812›Full record

ArticleGalen medical journal2022

SARS-CoV-2 RNA in Follicular Fluid, Granulosa Cells, and Oocytes of COVID-19 Infected Women Applying for Assisted Reproductive Technology : SARS-CoV-2 Detection in Follicular Fluid.

Sina Vakili, Amir Savardashtaki, Mohammad Ebrahim Parsanezhad, Zahra Mosallanezhad, Sedigheh Foruhari, Soudabeh Sabetian, Maryam Davari Zanjani, Mahnaz Banaei, Neda Pirbonyeh, Bahia Namavar Jahromi

Abstract read
In one paragraph

Article in Galen medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sina VakiliInfertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Amir SavardashtakiInfertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Mohammad Ebrahim ParsanezhadInfertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Zahra MosallanezhadInfertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Sedigheh ForuhariInfertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Soudabeh SabetianInfertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Maryam Davari ZanjaniStem Cells Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Mahnaz BanaeiIVF Center, Ghadir Mother and Child Hospital, Shiraz, Iran.
Neda PirbonyehDepartment of Microbiology, Burn and Wound Healing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Bahia Namavar JahromiInfertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Coronavirus disease 2019 (COVID-19) pandemic has raised concerns regarding the application of assisted reproductive technology (ART) in the world. Many ART programs have been delayed or continued with new precautions due to the ambiguity about vertical transmission and pregnancy safety. Regarding the possible risks of SARS-CoV-2 infection on ART and the resultant embryos, this study aimed to investigate the presence of SARS-CoV-2 in follicular fluid, granulosa cells, and oocytes of COVID-19-infected women undergoing ART. Materials and Methods: COVID-19-positive polymerase chain reaction tests were reported for five women undergoing ART cycles on the day of oocyte retrieval. SARS-CoV-2 tests were performed on oocytes, granulosa cells, and follicular fluid obtained from these COVID-19-infected women. Results: SARS-CoV-2 RNA was detected only in one follicular fluid sample; however, other follicular fluid samples, granulosa cells, and oocytes were negative regarding viral RNA. Conclusion: Given the unknown effects of COVID-19 on human reproduction and ART, strict precautions should be taken during the COVID-19 pandemic.

Indexed as

ARS-Cov-2Follicular FluidGranulosa CellOocyteReproduction

Identifiers

PMID42040812
PMCPMC12328006

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.