Evidence map›Paper›PMID 42040806›Full record

ReviewGalen medical journal2022

Review on Icariin as A Novel Medicaments to Confront Ovarian Cancer : Role of Icariin Against Ovarian Cancer.

Sima Mousavi, Solmaz Khastehband, Sahar Poudineh, Maryam Poudineh, Alireza Sarlak, Behnaz Barghgir, Sheida Jamalnia

Abstract readReview
In one paragraph

Review in Galen medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sima MousaviDepartment of Obstetrics and Gynecology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
Solmaz KhastehbandDepartment of Educational Management, Islamic Azad University-South Tehran Branch, Tehran, Iran.
Sahar PoudinehSchool of Medicine, Mashhad Azad University, Mashhad, Iran.
Maryam PoudinehSchool of Medicine, Mashhad Azad University, Mashhad, Iran.
Alireza SarlakSchool of Medicine, Hamedan University, Hamedan, Iran.
Behnaz BarghgirSchool of Medicine, Shahrud University, Shahrud, Iran.
Sheida JamalniaDepartment of Nursing and Midwifery, Kazeroun Branch, Islamic Azad University, Kazeroun, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer is described as one of the most common types of cancer and the leading cause of cancer-related deaths due to the high aggressiveness of this malignancy. However, the current therapeutically strategies failed to confront ovarian cancer or are accompanied by significant adverse effects leading to the recurrence of the disease and/or affecting the quality of life of survivors. On the other hand, ovarian cancer is recognized as a heterogenous disorder that is specified by alteration in a variety of molecular and cellular markers. Thereby, researchers are keen to find a novel therapeutical strategy representing high efficacy and safety, as well as be able to modulate altered biomolecules and signaling pathways. Icariin is a phytoestrogen with desired properties that are suggested for several chronic complications, particularly different types of cancer. The aim of the present study was to reveal the ameliorative characteristics of icariin and then discuss the antitumoral activities of this phytochemical against ovarian cancer with an emphasis on the modified molecular signaling pathways.

Indexed as

ApoptosisIcariinOvarian CancerPhytochemicalSurvival

Identifiers

PMID42040806
PMCPMC12327992

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.