Evidence map›Paper›PMID 42040758›Full record

ArticleFrontiers in reproductive health2026

Case Report: Rare case of first-trimester uterine rupture at 9 weeks' gestation following multiple hysteroscopic surgeries and a prior cesarean section.

Xiaomin Li, Shouxia Xie, Ling Zhang, Yaying Chu

Abstract readCase Reports
In one paragraph

Article in Frontiers in reproductive health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaomin LiDepartment of Obstetrics and Gynecology, Jiashan First People's Hospital, Jiaxing, China.
Shouxia XieDepartment of Obstetrics and Gynecology, Jiashan First People's Hospital, Jiaxing, China.
Ling ZhangDepartment of Obstetrics and Gynecology, Jiashan First People's Hospital, Jiaxing, China.
Yaying ChuDepartment of Obstetrics and Gynecology, Jiashan First People's Hospital, Jiaxing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uterine rupture is a rare but life-threatening obstetric emergency, with most cases occurring during late pregnancy or labor, particularly in patients with a history of uterine surgery. This report presents an exceptionally rare case of spontaneous uterine rupture at 9 weeks' gestation in a 36-year-old woman with a complex surgical history, including a midtrimester cesarean delivery for placenta accreta and multiple subsequent hysteroscopic adhesiolysis procedures. The patient presented with acute abdominal pain and hemorrhagic shock, highlighting the diagnostic challenges of early gestational rupture, in which ultrasonographic findings may be nonspecific. Despite initially inconclusive imaging, prompt laparoscopic intervention confirmed a 4-cm anterior uterine wall rupture with significant hemoperitoneum, enabling successful laparoscopic repair and preservation of reproductive potential. This case highlights several critical clinical insights, including the potential cumulative weakening effect of multiple uterine interventions beyond classical cesarean scarring, feasibility of minimally invasive management in hemodynamically stable patients, and importance of maintaining a high index of suspicion in high-risk populations regardless of gestational age. This atypical presentation challenges conventional understanding of uterine rupture timelines and risk stratification, emphasizing the need for individualized assessments of uterine integrity in patients with complex surgical histories. This report contributes to the limited literature on first-trimester uterine rupture and underscores the evolving paradigm of diagnostic and therapeutic approaches for this catastrophic obstetric complication.

Indexed as

acute and critical illnessearly pregnancyhemorrhagic shockintrauterine adhesionsuterine rupture

Identifiers

PMID42040758
PMCPMC13106293

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.