ArticleFrontiers in medicine2026
Comparison of short-term clinical efficacy between shoulder arthroplasty and plate fixation combined with bone cement augmentation for pathological fractures of the proximal humerus caused by metastatic tumors: a retrospective study of 40 cases.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The proximal humerus is an easily overlooked site for metastatic bone tumors, and pathological fractures here can cause severe pain and functional impairment. The selection of surgical regimens should take into account the location of bone metastases, the patient's physical status, and other relevant factors. Therefore, the optimal surgical strategy remains controversial. This study aimed to investigate and compare the clinical efficacy of two surgical approaches-tumor resection combined with prosthesis implantation versus plate fixation combined with bone cement augmentation-in patients with pathological fractures of the proximal humerus induced by metastatic tumors. By evaluating functional recovery, local tumor control, complications, and survival rate, this study clarified the applicable scenarios of the two surgical modalities, thereby providing a reference for clinical treatment decision-making. Methods: A retrospective analysis was performed on 40 patients with metastatic pathological fractures of the proximal humerus who were admitted to our institution from July 2017 to May 2025 (24 males and 16 females, with a mean age of 57 years). According to the surgical procedures, the patients were divided into two groups: the prosthesis group ( Results: A total of 40 patients were enrolled in this study, consisting of 15 cases in the prosthesis group and 25 cases in the plate-cement group. No significant differences were observed in gender, primary tumor type and fracture type between the two groups ( Conclusion: Plate fixation with bone cement augmentation provides superior short-term functional recovery and pain relief for metastatic proximal humeral fractures. However, these findings must be interpreted with caution due to the selection bias inherent in our non-randomized surgical approach.
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