ArticleACS omega2026
Potato Protein Isolate as a Solubility Enhancer of Poorly Water-Soluble Curcumin.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Limited aqueous solubility, often associated with low drug bioavailability, represents one of the greatest challenges in the clinical translation of numerous drugs currently on the market or in development. New and safer strategies are needed to unlock the full potential of poorly water-soluble compounds. Here, we report the ability of potato protein isolate (PPI), a valorized side-stream product of the potato starch industry, to arrest precipitation of curcumin in aqueous-based solutions in a concentration-dependent manner, leading to a manifold improvement in the solubility of curcumin as compared to pure water. High concentrations of PPI and presolubilization of curcumin (in pure ethanol) before mixing with the protein isolate were necessary to achieve complete solubilization of 0.1 mg/mL curcumin in 90% (v/v) water. The effect of PPI as a solubility enhancer was found to be limited by its propensity to undergo gel transition when exposed to higher concentrations of ethanol. Finally, PPI was non-toxic to HeLa cells, as demonstrated by an in
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Registered trials
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