Evidence map›Paper›PMID 42040345›Full record

SynthesisFrontiers in neuroscience2026

Functional and genetic divergence of aging-related

Shiqi Li, Yang Luo, Shasha Shi, Yan Ding

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shiqi Li *Department of Clinical Laboratory, Ningbo Psychiatric Hospital (The Affiliated Minkang Hospital of Ningbo University), Ningbo, China.
Yang Luo *Department of Cardiovascular Medicine, Province Wuyi County First People's Hospital, Zhejiang, China.
Shasha ShiDepartment of Clinical Laboratory, Province Wuyi County First People's Hospital, Zhejiang, China.
Yan DingDepartment of Clinical Laboratory, Chongqing Emergency Medical Center, School of Medicine, Chongqing University Central Hospital, Chongqing University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The etiology of late-onset Alzheimer's disease (AD) is only partly understood. Because Methods: A comprehensive literature search was conducted across five electronic databases. RevMan 5.1 was used for meta-analysis, including subgroup, meta-regression, and sensitivity analyses. To provide biological context, genome-wide data from IGAP/NIAGADS, AD-specific functional annotations from AGORA, and regulatory eQTL/sQTL evidence from GTEx were incorporated, with pathway enrichment using Enrichr. Results: Thirteen articles were included in the meta-analysis. Conclusion:

Indexed as

agingAlzheimer’s diseasemeta-analysismitochondrial dysfunctionpolymorphismTOMM40

Identifiers

PMID42040345
PMCPMC13106414

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.