Evidence map›Paper›PMID 42040342›Full record

ArticleFrontiers in neuroscience2026

Frequency shaping of tactile perception via transcutaneous interferential electrical stimulation: a simulation study.

Hiroki Ohara, Shunsuke Yoshimoto, Yasuyoshi Asai, Tomohiro Ota

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hiroki OharaGraduate School of Engineering, The University of Osaka, Suita, Japan.
Shunsuke YoshimotoGraduate School of Engineering, The University of Osaka, Suita, Japan.
Yasuyoshi AsaiProduct Analysis Center, Panasonic Holdings Corporation, Kadoma, Japan.
Tomohiro OtaProduct Analysis Center, Panasonic Holdings Corporation, Kadoma, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrotactile feedback via transcutaneous interferential electrical stimulation generates temporally modulated stimulation fields and enables frequency-domain adjustment with carrier and beat frequencies. To systematically characterize these effects, we present a simulation framework that integrates tissue-scale electrical potential simulation with the finite element method and axon-scale dynamics using the axon cable equation, which incorporates cable theory and the Hodgkin-Huxley model, to predict axon activation and tactile perceptual metrics. We simulated a simplified glabrous skin model with three orthogonally oriented axons. Results show that the carrier frequency in the range of 1-4 kHz determines the upper bounds of the perceived field size, reaching up to 1.6 mm and exceeding the 1 mm electrode diameter, and perceived intensity, whereas the beat frequency in the range of 0-100 Hz adjusts these quantities within these bounds. Furthermore, axons oriented perpendicular to the skin surface exhibit lower activation thresholds than those oriented parallel. Unlike the conventional approaches of transcutaneous electrical stimulation, our results suggest that transcutaneous interferential electrical stimulation can shape the perceived field and perceived intensity without electrode reconfiguration or amplitude modulation. These findings clarify the distinct roles of carrier and beat frequency in tactile perception. This paper provides a theoretical foundation for frequency-domain adjustment of electrotactile interfaces and points toward compact, programmable systems. Quantitative validation through psychophysical experiments will further test and refine these predictions.

Indexed as

axon cable equationcable theorycomputational simulationelectrotactile feedbackglabrous skinHodgkin–Huxley modelmechanoreceptortranscutaneous electrical stimulation

Identifiers

PMID42040342
PMCPMC13102772

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.