Evidence map›Paper›PMID 42040037›Full record

ReviewGalen medical journal2024

A State of Art Review: Volatile Organic Compounds and Periodontitis.

Mohammad Ghasemirad, Omid Tavakol, Soroush Etesami, Kiana Nikeghbal, Dorsa Nikeghbal, Fatemeh Abedi Diznab, Reza Mahmoudi Anzabi

Abstract readReview
In one paragraph

Review in Galen medical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohammad GhasemiradDepartment of Periodontics, Faculty of Dentistry, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Omid TavakolDepartment of Prosthodontist, Faculty of Dentistry, Shiraz Branch, Islamic Azad University, Shiraz, Iran.
Soroush EtesamiDepartment of Periodontics, School of Dentistry, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Kiana NikeghbalDepartment of Oral and Maxillofacial Radiology, School of Dentistry, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Dorsa NikeghbalDepartment of Oral and School of Maxillofacial Surgery, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Fatemeh Abedi DiznabDepartment of Orthodontics, Faculty of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Reza Mahmoudi AnzabiDepartment of Oral and School of Maxillofacial Surgery, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontitis is a notable public health issue impacting more than 1 billion individuals globally, and its connection with volatile organic compounds (VOCs) has attracted growing interest. This review seeks to explore the existing knowledge on the link between VOCs and periodontitis. MATERIALS AND

methodsAn extensive literature review was performed to pinpoint key VOCs associated with periodontitis.

resultsThe review revealed that several VOCs, such as hydrogen sulfide, methanethiol, indole, limonene, formaldehyde, 1,4-dichlorobenzene, 2-Aminothiazoline-4-carboxylic acid, ethyl acetate, methyl mercaptan, dimethyl sulfide, acetone, pyridine, picolines, o-xylene, mandelic acid, and N-acetyl-S-(4-hydroxy-2-butenyl)-L-cysteine, are linked to periodontitis, with some contributing to heightened oral infection, direct tissue harm, oral malodor, and inflammatory responses, while the causality of this phenomenon remains unclear as it is uncertain which event occurs first.

conclusionThis review enumerates the VOCs that may either contribute to or arise from periodontitis; hydrogen sulfide appears to be the most extensively studied VOC in the context of periodontitis. This review highlights the intricate relationship between VOCs and periodontitis and underscores the necessity for additional research to clarify the mechanisms underlying this association and to guide the creation of effective prevention and treatment strategies.

Indexed as

Hydrogen SulfideMethanethiolPeriodontitisVolatile Organic Compounds

Identifiers

PMID42040037
PMCPMC12107334

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.