ArticleInternational journal of ophthalmology2026
Long-term observation of the endothelium morphology and corneal thickness in myopic adolescents treated with orthokeratology: a 10-year retrospective study.
Article in International journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Association between first-year axial elongation and 10-year myopia progression in children wearing orthokeratology lenses: a ten-year longitudinal study.Frontiers in cell and developmental biology · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo assess the long-term safety of orthokeratology (ortho-k) in myopic children by evaluating changes in corneal endothelial morphology and central corneal thickness (CCT) after prolonged ortho-k lens wear.
methodsThis study included 65 myopic children (130 eyes). The ortho-k group comprised 39 children who had worn ortho-k lenses for more than 10y. The control group included 26 children who wore single-vision spectacles for myopia correction. Clinical data and adverse events were documented throughout the follow-up period. Endothelial cell density (ECD), coefficient of variation (CV) of cell area, percentage of hexagonal cells (%SIX), and CCT were measured at baseline and at the final follow-up visit.
resultsThe 39 participants (18 males, 21 females) enrolled in the ortho-k group completed the 10-year follow-up examinations successfully. The ages ranged from 7 to 12 (9.24±1.26)y. In the control group, 26 participants (13 males, 13 females) were successfully recalled and completed their 10
conclusionThis 10-year retrospective study demonstrates that long-term ortho-k lens wear has no significant adverse effects on corneal endothelial morphology or CCT compared with spectacle wear. Ortho-k shows excellent long-term safety with regard to corneal endothelial parameters and CCT, comparable to that of conventional spectacle correction in myopic children.
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Registered trials
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