ArticleFrontiers in oral health2026
Effects of
Article in Frontiers in oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Polyphenol-containing mouth rinses are known to improve the protective properties of the dental pellicle against acids by increasing its thickness and density. Even though Methods: Transmission electron microscopy (TEM) and atomic adsorption spectrometry (AAS) were used to visualize the ultrastructure of the 6-min and 120-min pellicle as well as measure the calcium release of the enamel surface after rinsing for 1 min with WSLE or water as control and applying different acidic challenges (1% citric acid, 0.01 M HCl or water). Results: Mouth rinsing with WSLE did neither increase thickness or density of the pellicle nor improve its protectivity against acids. Compared to water-rinsing, samples showed equal or even higher dissolution of the pellicle upon acidic attack. AAS experiments demonstrated an increased calcium release and the leaf extract was shown to possess an appreciable calcium content. Conclusion: WSLE represents an outlier in the group of polyphenol-containing mouth rinses in terms of its effects on the dental pellicle. The increased calcium release upon rinsing and its appreciable calcium content suggests it may act as a calcium source for the dental pellicle. Clinical significance: Based on its previously demonstrated anti-adhesive properties on the oral biofilm and the current results on its remarkable calcium content, WSLE presents as a promising candidate for daily mouth rinse use, warranting further clinical studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.