Evidence map›Paper›PMID 42039912›Full record

ArticleOsteoarthritis and cartilage open2026

Measures of resting cartilage structure and composition in runners with and without knee osteoarthritis.

Michael A Hunt, Michaela C M Khan, Natasha M Krowchuk, Anthony A Gatti, Alexander Rauscher, Jean-Francois Esculier

Abstract read
In one paragraph

Article in Osteoarthritis and cartilage open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael A HuntMotion Analysis and Biofeedback Laboratory, University of British Columbia, Vancouver, BC, Canada.
Michaela C M KhanMotion Analysis and Biofeedback Laboratory, University of British Columbia, Vancouver, BC, Canada.
Natasha M KrowchukMotion Analysis and Biofeedback Laboratory, University of British Columbia, Vancouver, BC, Canada.
Anthony A GattiNeuralSeg Ltd., Hamilton, ON, Canada.
Alexander RauscherDepartment of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada.
Jean-Francois EsculierDepartment of Physical Therapy, University of British Columbia, Vancouver, BC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To compare measures of resting cartilage structure and composition in experienced older runners with and without knee osteoarthritis. Design: 47 runners (mean (sd) age = 58.0 (8.4) years) with knee osteoarthritis, as well as 27 runners (mean (sd) age = 52.2 (9.7) years) with no radiographic knee osteoarthritis or knee pain participated. Magnetic resonance imaging was used to measure cartilage structure and composition and calculate: volume and thickness, as well as T2 and T1ρ relaxation times, for eight regions of interest. Between-group comparisons were examined using analysis of covariance with body mass, years of self-reported running experience, and average weekly running volume over the three months prior to testing included as covariates. Results: Few between-group differences were observed. Runners with knee osteoarthritis exhibited less patellar cartilage thickness (mean difference [95% confidence limits]: -0.3 [-0.4, -0.1] mm) and volume (-408 [-736, -79] mm Conclusions: Our findings do not support the notion of widespread cartilage degeneration in the knees of experienced older runners with knee osteoarthritis. Longitudinal research is necessary to examine the longer-term impacts of running on general knee health in runners with and without knee osteoarthritis.

Indexed as

CartilageKneeOsteoarthritisRunning

Identifiers

PMID42039912
PMCPMC13103553

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.