Evidence map›Paper›PMID 42039889›Full record

SynthesisFrontiers in nutrition2026

Plant-derived alginate polysaccharide hydrogels in sport and exercise nutrition: implications for carbohydrate metabolism, gastrointestinal integrity, exercise recovery, and athletic performance.

Pengyuan Li, Qingwei Song, Nannan Xu

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pengyuan LiSchool of Sport and Health, Zhumadian Preschool Education College, Zhumadian, Henan, China.
Qingwei SongSchool of Biotechnology and Food Science, Tianjin University of Commerce, Tianjin, China.
Nannan XuSchool of Sport and Health, Zhumadian Preschool Education College, Zhumadian, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Alginate is a plant-derived polysaccharide used in sport nutrition for its gel-forming properties. Alginate- and pectin-based carbohydrate hydrogels aim to optimize carbohydrate delivery during endurance exercise by modulating gastric emptying and intestinal absorption. However, evidence on their effects on metabolism, gastrointestinal (GI) tolerance, recovery, and performance remains inconsistent. Objective: To systematically evaluate the effects of alginate-based carbohydrate hydrogels on metabolic responses, GI tolerance, recovery, and endurance performance in humans. Methods: PubMed, Scopus, Web of Science, SPORTDiscus, and Google Scholar were searched for randomized controlled trials (2000-2025) comparing alginate- or alginate-pectin-based hydrogels with non-hydrogel carbohydrate or placebo during ≥60-min endurance exercise. Outcomes on metabolism, GI symptoms, recovery, and performance were qualitatively synthesized and visualized via an evidence heatmap. Results: Nine trials met inclusion criteria. Hydrogels generally enhanced metabolic indicators such as exogenous carbohydrate oxidation, particularly at high ingestion rates. GI tolerance was similar to traditional solutions, with fewer symptoms reported under high-carbohydrate conditions. Performance effects were inconsistent-minor improvements occurred mainly in running, with limited or null effects in cycling and skiing. Preliminary evidence indicates potential attenuation of muscle damage markers and preserved post-exercise amino acid availability. Conclusion: Alginate-based hydrogels appear to modulate carbohydrate metabolism without consistently improving endurance performance. Their efficacy depends on exercise type, carbohydrate dose, and athlete training status. Further well-controlled trials are needed to define their role in supporting performance and recovery.

Indexed as

carbohydrate hydrogelendurance performanceexercise recoverygastrointestinal integritysport and exercise nutrition

Identifiers

PMID42039889
PMCPMC13106452

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.