ArticleFrontiers in nutrition2026
The preoperative albumin-to-carcinoembryonic antigen ratio (ACR) predicts prognosis and facilitates risk stratification in gastric cancer: a retrospective cohort study.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: This study aimed to evaluate the association between the preoperative albumin-to-carcinoembryonic antigen ratio (ACR) and clinicopathological characteristics as well as the association between ACR and prognosis in gastric cancer, so as to provide evidence for improved risk stratification and personalized management. Methods: Clinicopathological data of gastric cancer patients who underwent radical gastrectomy at Shanxi Province Cancer Hospital between December 2015 and January 2017 were retrospectively reviewed. Following patient follow-up, Cox proportional-hazards regression was used to identify prognostic factors for overall survival (OS) and disease-free survival (DFS). An ACR-incorporated nomogram was developed, and its predictive accuracy was evaluated using the concordance index (C-index) and calibration curves. Its discriminative ability was further compared against that of the conventional TNM staging system. Results: Among the 1,161 enrolled patients, 192 (16.5%) and 969 (83.5%) were classified into low- and high-ACR groups, respectively. Low ACR was correlated with adverse pathological features and inferior survival outcomes. Both OS and DFS were significantly shorter in the low-ACR group (both Conclusion: Preoperative low ACR is significantly associated with aggressive tumor biology and poor survival in gastric cancer. The ACR-based nomogram serves as a clinically useful tool for prognostic prediction, risk stratification, and the guidance of personalized therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.