Evidence map›Paper›PMID 42039763›Full record

ArticleFood science & nutrition2026

Phytobiotic Essential Oils as Antibiotic Alternatives in Aquaculture: Antimicrobial and Antioxidant Properties of Garlic, Thyme, Thyme Conehead, Rosemary, and Eucalyptus.

Calinoiu Lavinia Florina, Plamada Diana, Teleky Bernadette-Emoke, Stefanescu Bianca-Eugenia, Chrysanthos Stergiopoulos, Magdalini Krokida, Ioannis Maramathas, Papadaki Sofia, Moustogianni Anna, Panagiota Anagnostopoulou and 1 more

Abstract read
In one paragraph

Article in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Calinoiu Lavinia FlorinaDepartment of Food Science, Faculty of Food Science and Technology University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca Cluj-Napoca Romania.
Plamada DianaInstitute of Life Sciences University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca Cluj-Napoca Romania.
Teleky Bernadette-EmokeInstitute of Life Sciences University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca Cluj-Napoca Romania.ORCID https://orcid.org/0000-0003-3672-8717
Stefanescu Bianca-EugeniaInstitute of Life Sciences University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca Cluj-Napoca Romania.
Chrysanthos StergiopoulosNational Technical University of Athens, School of Chemical Engineering, Laboratory of Process Analysis and Design Zografou Athens Greece.ORCID https://orcid.org/0000-0001-6002-4870
Magdalini KrokidaNational Technical University of Athens, School of Chemical Engineering, Laboratory of Process Analysis and Design Zografou Athens Greece.
Ioannis MaramathasDignity Private Company Zografou Athens Greece.
Papadaki SofiaDignity Private Company Zografou Athens Greece.
Moustogianni AnnaZoonomi S.A. Perigiali Korinthias Greece.
Panagiota AnagnostopoulouZoonomi S.A. Perigiali Korinthias Greece.
Vodnar Dan CristianDepartment of Food Science, Faculty of Food Science and Technology University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca Cluj-Napoca Romania.ORCID https://orcid.org/0000-0001-5407-8071

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing threat of antimicrobial resistance in aquaculture demands sustainable alternatives to conventional antibiotics. Plant-derived essential oils are attractive candidates owing to their antimicrobial, antioxidant, and immunomodulatory activities, yet their volatility and chemical instability hinder incorporation into aquafeeds. This study integrated chemical profiling, bioactivity assessment, and spray-drying microencapsulation to evaluate five Eos, garlic, thyme, conehead thyme, rosemary, and eucalyptus, as functional feed additives (illustrated in the Graphical abstract below). Gas chromatography-mass spectrometry (GC-MS) revealed distinct chemotypes: garlic oil was rich in propyl propane thiosulfonate (30.3%); thyme oil in thymol (35.1%) and p-cymene (31.6%); conehead thyme oil in carvacrol (19.9%); rosemary oil in eucalyptol (43.0%); and eucalyptus oil in eucalyptol (68.9%). Antioxidant capacity varied markedly, with conehead thyme (34.7 μmol/mL) and garlic (17.8 μmol/mL) outperforming thyme (12.7 μmol/mL), while rosemary (0.79 μmol/mL) and eucalyptus (0.32 μmol/mL) were weak. Antimicrobial testing showed potent activity for garlic and both thyme oils against

Indexed as

antimicrobialantioxidantaquacultureencapsulationessential oilsionic gelationspray drying

Identifiers

PMID42039763
PMCPMC13107120

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.