Evidence map›Paper›PMID 42039699›Full record

ArticleFrontiers in genetics2026

Unraveling quantitative trait loci (QTL) overlapping epigenomic regulatory regions associated with feeding behavior in pigs.

Izally Carvalho Gervásio, Luiz F Brito, Andre C Araujo, Simara Larissa Fanalli, Bárbara Silva-Vignato, Artur O Rocha, Lorena Ferreira Benfica, Leticia Fernanda de Oliveira, Andrezza Maria Felício Ament, Gabriel Costa Monteiro Moreira and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Izally Carvalho GervásioDepartment of Food Science and Technology, Luiz de Queiroz College of Agriculture (ESALQ), University of São Paulo, São Paulo, Brazil.
Luiz F BritoDepartment of Animal Sciences, Purdue University, West Lafayette, IN, United States.
Andre C AraujoAcuFast Swine, Saskatoon, SK, Canada.
Simara Larissa FanalliCollege of Animal Science and Food Engineering (FZEA), University of São Paulo, São Paulo, Brazil.
Bárbara Silva-VignatoDepartment of Food Science and Technology, Luiz de Queiroz College of Agriculture (ESALQ), University of São Paulo, São Paulo, Brazil.
Artur O RochaDepartment of Animal Sciences, Purdue University, West Lafayette, IN, United States.
Lorena Ferreira BenficaDepartment of Animal Sciences, Purdue University, West Lafayette, IN, United States.
Leticia Fernanda de OliveiraDepartment of Animal Sciences, Purdue University, West Lafayette, IN, United States.
Andrezza Maria Felício AmentDepartment of Food Science and Technology, Luiz de Queiroz College of Agriculture (ESALQ), University of São Paulo, São Paulo, Brazil.
Gabriel Costa Monteiro MoreiraInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (INRAE), Igny, Île-de-France, France.
Cristina Tschorny Moncau-GadbemFaculty of Veterinary Medicine and Animal Science (FMVZ), University of São Paulo, São Paulo, Brazil.
Aline Silva Mello CesarDepartment of Food Science and Technology, Luiz de Queiroz College of Agriculture (ESALQ), University of São Paulo, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Feed behavior traits are directly linked to the sustainability of pig production. This study aimed to investigate the genetic basis of feeding behavior traits in Landrace and Yorkshire pigs, focusing on genomic regions, quantitative trait loci (QTL), candidate genes, and metabolic pathways associated with these traits. Methods: Genome-wide association studies (GWAS) were performed, followed by functional enrichment analyses and integrative bioinformatics approaches to identify biologically relevant genomic regions, candidate genes, and pathways associated with feeding behavior traits. Results: Several candidate genes and transcription factors were identified, including STAT3, STAT5A, STAT5B, RARA, SMAD4, MYC, FOXP3, SP1, NOTCH1, and RXRA. In addition, strong candidate genes such as SLC22A2, CPAMD8, and NKX2-6 were highlighted as potentially influencing feeding behavior traits. Discussion: These findings improve the understanding of the genomic architecture underlying feeding behavior traits and provide valuable insights for the development of more efficient breeding programs, contributing to improved animal production efficiency and welfare.

Indexed as

functional genomicsgenetic markersintegrative genomics viewer genome browserpig breedingSNP mapping

Identifiers

PMID42039699
PMCPMC13105475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.