Evidence map›Paper›PMID 42039667›Full record

ArticlebioRxiv : the preprint server for biology2026

NPP-21/TPR is required for developmental control of spindle checkpoint strength in

Natalie Gallagher, Shevelle Brown, Valentin Duprat, Simone Köhler, Abby F Dernburg, Needhi Bhalla

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natalie GallagherDepartment of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064.
Shevelle BrownDepartment of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064.
Valentin DupratDepartment of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064.
Simone KöhlerDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720.ORCID 0000-0002-1119-8855
Abby F DernburgDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720.ORCID 0000-0001-8037-1079
Needhi BhallaDepartment of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064.ORCID 0000-0002-6859-0073

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Crossover control during meiosisR01GM065591 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI DERNBURG, ABBY F · 2002 to 2021
$4.5M
Training Program in Molecular, Cell, and Developmental BiologyT32GM133391 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI Needhi Bhalla · 2019 to 2026
$3.0M
Supplement to support an undergraduate student on Cell Cycle Control in C. elegansR35GM141835 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI BHALLA, NEEDHI · 2021 to 2025
$2.5M
NIGMS NIH HHS R01 GM065591NIGMS NIH HHS R35 GM141835NIGMS NIH HHS T32 GM133391NIH HHS P40 OD010440
6 · The paper itself

Abstract

The spindle checkpoint ensures accurate chromosome segregation by monitoring whether chromosomes, via kinetochores, are properly attached to the spindle. If chromosomes fail to establish bipolar attachment, the checkpoint delays the cell cycle to enable error correction. In

Identifiers

PMID42039667
PMCPMC13104992

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.