Evidence map›Paper›PMID 42039642›Full record

ArticlebioRxiv : the preprint server for biology2026

The Effects of Phosphorylation on the Structure and Function of Motif A, an Intrinsically Disordered Region within SIRT1.

Sabrina M Richter, Hoang-Long Bui, Addison Chen, Chloe Tannous, Benjamin R Butler, Sophia D Bennett, Samson Quang-Anh Nguyen, Justin Prado, Ayan Mohamed, Isaac A DuBois and 8 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Sabrina M RichterDepartment of Chemistry, San José State University, San José, CA, 95112.ORCID 0009-0009-3066-3685
Hoang-Long BuiDepartment of Chemistry, San José State University, San José, CA, 95112.
Addison ChenDepartment of Chemistry, San José State University, San José, CA, 95112.
Chloe TannousDepartment of Chemistry, San José State University, San José, CA, 95112.
Benjamin R ButlerDepartment of Chemistry, San José State University, San José, CA, 95112.
Sophia D BennettDepartment of Chemistry, San José State University, San José, CA, 95112.
Samson Quang-Anh NguyenDepartment of Chemistry, San José State University, San José, CA, 95112.
Justin PradoDepartment of Chemistry, San José State University, San José, CA, 95112.
Ayan MohamedDepartment of Chemistry, San José State University, San José, CA, 95112.
Isaac A DuBoisDepartment of Chemistry, Grand Valley State University, Allendale, MI.
Emile TadrosDepartment of Chemistry, Grand Valley State University, Allendale, MI.
Nhu Tam ThaiDepartment of Chemistry, San José State University, San José, CA, 95112.
Selina Lima GuanDepartment of Chemistry, San José State University, San José, CA, 95112.
Carla Marie PeraltaDepartment of Chemistry, San José State University, San José, CA, 95112.
Andy KwongDepartment of Chemistry, San José State University, San José, CA, 95112.
Laura M L HawkDepartment of Chemistry, Grand Valley State University, Allendale, MI.ORCID 0000-0001-7176-3863
Gianmarc GrazioliDepartment of Chemistry, San José State University, San José, CA, 95112.ORCID 0000-0003-2559-5103
Ningkun WangDepartment of Chemistry, San José State University, San José, CA, 95112.ORCID 0000-0003-3545-5323

Funding

Probing Amyloid Fibril Self-Assembly with Network Hamiltonian Simulations in Explicit SpaceR16GM150706 · NIGMS · SAN JOSE STATE UNIVERSITY · PI Gianmarc Grazioli · 2023 to 2026
$714k
Elucidating the Mechanism for Allosteric Regulation of SIRT1 through the N-Terminal RegionR16GM149377 · NIGMS · SAN JOSE STATE UNIVERSITY · PI Ningkun Wang · 2023 to 2026
$682k
Circular Dichroism SpectrophotometerS10GM154297 · NIGMS · SAN JOSE STATE UNIVERSITY · PI WANG, NINGKUN · 2024 to 2024
$186k
NIGMS NIH HHS R16 GM149377NIGMS NIH HHS R16 GM150706NIGMS NIH HHS S10 GM154297
6 · The paper itself

Abstract

The NAD

Indexed as

Intrinsically Disordered RegionsLysine DeacetylasePhosphorylation

Identifiers

PMID42039642
PMCPMC13104807

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.