Evidence map›Paper›PMID 42039481›Full record

ArticlebioRxiv : the preprint server for biology2026

Efficacy of Purified Borrelial Lipoproteins (PBL) as an oral formulation in reducing transmission of Lyme spirochetes from reservoir hosts to

Venkatesh Kumaresan, Jolie F Starling-Lin, Taylor MacMackin Ingle, Nathan Kilgore, J Seshu

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Venkatesh KumaresanSouth Texas Center for Emerging Infectious Diseases, Department of Molecular Microbiology and Immunology, The University of Texas at San Antonio San Antonio, TX-78249.
Jolie F Starling-LinSouth Texas Center for Emerging Infectious Diseases, Department of Molecular Microbiology and Immunology, The University of Texas at San Antonio San Antonio, TX-78249.
Taylor MacMackin IngleSouth Texas Center for Emerging Infectious Diseases, Department of Molecular Microbiology and Immunology, The University of Texas at San Antonio San Antonio, TX-78249.
Nathan KilgoreSouth Texas Center for Emerging Infectious Diseases, Department of Molecular Microbiology and Immunology, The University of Texas at San Antonio San Antonio, TX-78249.
J SeshuSouth Texas Center for Emerging Infectious Diseases, Department of Molecular Microbiology and Immunology, The University of Texas at San Antonio San Antonio, TX-78249.ORCID 0000-0002-4471-2435

Funding

Efficacy of novel reservoir-host targeted bait formulations against a tick-borne pathogenR01AI152233 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI SESHU, JANAKIRAM · 2021 to 2025
$1.9M
MMI-T32 Training Pre-doctoral Scientists in Molecular Microbiology and Immunology at UTSAT32AI184340 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI Astrid E Cardona, Jose L. Lopez-Ribot · 2024 to 2026
$463k
NIAID NIH HHS R01 AI152233NIAID NIH HHS T32 AI184340
6 · The paper itself

Abstract

Blocking transmission of

Indexed as

antibody responseLyme diseaseOral vaccine formulationPeromyscus leucopusPurified Borrelial Lipoproteinstick-pathogen-reservoir axis

Identifiers

PMID42039481
PMCPMC13104960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.