ArticlebioRxiv : the preprint server for biology2026
Non-invasive Neuromodulation Targeting Approach by Mapping Stimulations and Lesions That Modify Visual Memory.
Simon Kwon, Soyoung Lee, Joshua S Siegel, Nicole Chiulli, Michael Freedberg, Melissa Hebscher, Joshua Hendrikse, Molly S Hermiller, Gong-Jun Ji, Arielle Tambini and 6 more
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
16 authors.
Simon KwonMass General Brigham, USA.
Soyoung LeeMass General Brigham, USA.
Joshua S SiegelNew York University, USA.
Nicole ChiulliMass General Brigham, USA.
Melissa HebscherUniversity of Chicago, USA.
Joshua HendrikseMonash University, Australia.
Molly S HermillerFlorida State University, USA.
Gong-Jun JiAnhui Medical University, China.
Arielle TambiniNathan Kline Institute for Psychiatric Research, USA.
Eyre YeBeijing Normal University, China.
Shira Cohen-ZimermanNorthwestern University, USA.
Maurizio CorbettaUniversity of Padua, Italy.
Jordan GrafmanNorthwestern University, USA.
Joel L VossUniversity of Chicago, USA.
Funding
Using human brain connectivity to identify the causal neuroanatomical substrate of depression symptomsR01MH113929 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI MICHAEL D FOX · 2017 to 2026
$6.9MRepetitive TMS-induced modulation of cortical excitability in ADR01MH115949 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SHAFI, MOUHSIN · 2018 to 2022
$3.2MTreating hyperexcitability in Alzheimer’s disease with levetiracetam to improve brain function and cognitionR01AG060987 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SHAFI, MOUHSIN · 2019 to 2023
$3.0MPersonalized circuit-based neuromodulation targets for depressionK23MH121657 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI SIDDIQI, SHAN · 2020 to 2024
$978kDeriving TMS Targets for Mood Valence and Mood Stabilization in Bipolar DisorderK23MH129829 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI Joseph Jeffrey Taylor · 2022 to 2026
$978kTransdiagnostic memory, mood and motor circuits in Alzheimer's and neurodegenerative diseaseR56AG069086 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI FOX, MICHAEL D · 2021 to 2021
$873kTargeted modulation of symptom-specific brain circuits with transcranial magnetic stimulationR21MH126271 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI FOX, MICHAEL D · 2021 to 2022
$492kKetamine for the treatment for alcohol use disorder in the emergency department: A pilot double-blind, placebo-controlled randomized clinical trialR21AA030372 · NIAAA · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAI, PETER R, SUZUKI, JOJI · 2022 to 2023
$470kCSRD VA I01 CX002293NIAAA NIH HHS R21 AA030372NIA NIH HHS R01 AG060987NIA NIH HHS R56 AG069086NIMH NIH HHS K23 MH121657NIMH NIH HHS K23 MH129829NIMH NIH HHS R01 MH113929NIMH NIH HHS R01 MH115949NIMH NIH HHS R21 MH126271
6 · The paper itselfAbstract
Therapeutic brain stimulation is believed to target specific networks, but targeting approaches for memory remain debated. For other symptoms, neuromodulation targets have been localized by mapping connectivity of lesions and stimulation sites to specific symptoms. This approach has yielded networks for global memory, but it remains unclear whether it applies to specific types of memory. Here, we mapped connectivity of stimulation sites, lesions, and atrophy patterns associated with different memory types. We included 544 individuals across three datasets: transcranial magnetic stimulation (
Identifiers
PMID42039451
PMCPMC13105042
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