In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
17 authors.
Smruti R RoutInstitute for Auditory Neuroscience, University Medical Center Göttingen, 37077 Göttingen, Germany.ORCID 0009-0003-4143-5473 Martin KulkeCenter for Functional Protein Assemblies, Technical University of Munich, 85748 Garching, Germany.ORCID 0000-0002-2689-2428 Maxim DroemerFaculty for Chemistry and Pharmacy, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.ORCID 0009-0009-5280-2041 Marcel WendelDepartment of Biology, University of Konstanz, 78457 Konstanz, Germany.
Tat Cheung ChengInstitute for Neuropathology, University Medical Center Göttingen, 37073 Göttingen, Germany.ORCID 0000-0003-2801-3084 Tristan A MauckCenter for Functional Protein Assemblies, Technical University of Munich, 85748 Garching, Germany.ORCID 0009-0003-0862-1725 Sean AsgariDepartment of Biomedical Sciences, Florida State University College of Medicine, 1115 W. Call St., Tallahassee, FL 32306, USA.
Antonia A NemecDepartment of Biomedical Sciences, Florida State University College of Medicine, 1115 W. Call St., Tallahassee, FL 32306, USA.ORCID 0000-0001-6060-1666 Mikhail SheinFaculty for Chemistry and Pharmacy, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
Yusuke SatoDepartment of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University, 4-101 Koyama-cho Minami, Tottori-shi, Tottori 680-8552, Japan.
Shuya FukaiDepartment of Chemistry, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan.
Gregor WitteGene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.ORCID 0000-0003-0313-0962 Robert J TomkoDepartment of Biomedical Sciences, Florida State University College of Medicine, 1115 W. Call St., Tallahassee, FL 32306, USA.ORCID 0000-0003-2515-1078 Martin ZachariasCenter for Functional Protein Assemblies, Technical University of Munich, 85748 Garching, Germany.ORCID 0000-0001-5163-2663 Anne K SchuetzFaculty for Chemistry and Pharmacy, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.ORCID 0000-0001-6398-5757 Eri SakataInstitute for Auditory Neuroscience, University Medical Center Göttingen, 37077 Göttingen, Germany.ORCID 0000-0002-8580-3683 Funding
Engagement and Communication Between Proteasonal SubcomplexesR01GM118600 · NIGMS · FLORIDA STATE UNIVERSITY · PI ROBERT JOSEPH TOMKO · 2017 to 2026
$2.7MNIGMS NIH HHS R01 GM118600
6 · The paper itselfAbstract
The multifunctional AAA+ ATPase p97/VCP is a pivotal regulator of cellular proteostasis, extracting polyubiquitinated substrates from protein complexes or organelle membranes for proteasomal degradation. Mutations in p97 are linked to a broad spectrum of neurodegenerative disorders, including multisystem proteinopathy and amyotrophic lateral sclerosis. Here, we provide insights into the basis of dysfunction in p97
Identifiers
PMID42039423
PMCPMC13104809
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