Evidence map›Paper›PMID 42039301›Full record

ArticleFrontiers in transplantation2026

Uterus transplantation in the United States: analysis of patients and early postoperative outcomes in the national organ procurement and transplantation network.

Thomas Schaschinger, Leonard Knoedler, Tobias Niederegger, Gabriel Hundeshagen, Olivier Mathieu, Lucile Cabanel, Michel G Cazenave, Samuel Knoedler, Curtis L Cetrulo, Alexandre G Lellouch

Abstract read
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In one paragraph

Article in Frontiers in transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Thomas SchaschingerDepartment of Oral and Maxillofacial Surgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Leonard KnoedlerDepartment of Oral and Maxillofacial Surgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Tobias NiedereggerDepartment of Oral and Maxillofacial Surgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Gabriel HundeshagenDepartment of Hand-, Plastic and Reconstructive Surgery, Microsurgery, Burn Trauma Center. BG Trauma Center Ludwigshafen, University of Heidelberg, Heidelberg, Germany.
Olivier MathieuDepartment of Plastic, Reconstructive and Aesthetic Surgery, Cedars Sinai Hospital, Los Angeles, CA, United States.
Lucile CabanelVascularized Composite Allotransplantation Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Michel G CazenaveGynecology Department, Hôpital Cochin-Port Royal, Assistance Publique - Hôpitaux de Paris, Paris, France.
Samuel KnoedlerDepartment of Plastic Surgery and Hand Surgery, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
Curtis L CetruloDepartment of Plastic, Reconstructive and Aesthetic Surgery, Cedars Sinai Hospital, Los Angeles, CA, United States.
Alexandre G LellouchDepartment of Plastic, Reconstructive and Aesthetic Surgery, Cedars Sinai Hospital, Los Angeles, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Uterus Vascularized Composite Allotransplantation (UTx) offers a solution for individuals with uterine factor infertility to enable pregnancy. This exploratory retrospective study evaluates adverse postoperative outcomes in UTx recipients in the U.S. using data from the Organ Procurement and Transplantation Network (OPTN) to identify potential risk factors. Methods: Data from the OPTN database were analyzed for 55 patients who underwent UTx in the U.S. Due to missing outcome data, 15 cases were excluded, resulting in a final cohort of 40 patients (73%) eligible for outcome analysis. Variables such as the number of acute rejection (AR) episodes, hospitalizations, and complications were assessed to determine associations with patient related risk factors. Results: Among the 40 recipients with a mean age of 31 ± 4.7 years, 24 (60%) received grafts from living donors and 16 (40%) from deceased donors. The 12 AR episodes [median 0.0 (IQR 0.0-0.25)] were significantly associated with increased BMI ( Conclusions: This study provides insights into adverse postoperative outcomes in UTx recipients, highlighting the impact of higher BMI, donor status, and warm ischemia time on AR, hospitalizations, and complications.

Indexed as

OPTNorgan procurement and transplantation networkuterus transplantationvascularized composite allotransplantationVCA

Identifiers

PMID42039301
PMCPMC13106351

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