Evidence map›Paper›PMID 42039278›Full record

ArticleActa pharmaceutica Sinica. B2026

Engineered apoptotic vesicle mimetics with tunable "eat-me" signaling precisely regulate tumor-associated macrophages for potentiating cancer immunotherapy.

Yu Liu, Chunbai Xiang, Yeneng Dai, Chao Li, Michael N Okeke, Ting Jiang, Xing Yang, Yehuda G Assaraf, Kai Miao, Yue Wang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yu LiuMoE Frontiers Science Center for Precision Oncology, Cancer Center, Faculty of Health Sciences, University of Macau, Taipa, Macau 999078, China.
Chunbai XiangKey Laboratory of Biomedical Imaging Science and System, Chinese Academy of Sciences, State Key Laboratory of Biomedical Imaging Science and System, Guangdong Key Laboratory of Nanomedicine, CAS-HK Joint Lab for Biomaterials, Shenzhen Institutes of Advanced Technology, Shenzhen 518055, China.
Yeneng DaiMoE Frontiers Science Center for Precision Oncology, Cancer Center, Faculty of Health Sciences, University of Macau, Taipa, Macau 999078, China.
Chao LiKey Laboratory of Biomedical Imaging Science and System, Chinese Academy of Sciences, State Key Laboratory of Biomedical Imaging Science and System, Guangdong Key Laboratory of Nanomedicine, CAS-HK Joint Lab for Biomaterials, Shenzhen Institutes of Advanced Technology, Shenzhen 518055, China.
Michael N OkekeKey Laboratory of Biomedical Imaging Science and System, Chinese Academy of Sciences, State Key Laboratory of Biomedical Imaging Science and System, Guangdong Key Laboratory of Nanomedicine, CAS-HK Joint Lab for Biomaterials, Shenzhen Institutes of Advanced Technology, Shenzhen 518055, China.
Ting JiangKey Laboratory of Biomedical Imaging Science and System, Chinese Academy of Sciences, State Key Laboratory of Biomedical Imaging Science and System, Guangdong Key Laboratory of Nanomedicine, CAS-HK Joint Lab for Biomaterials, Shenzhen Institutes of Advanced Technology, Shenzhen 518055, China.
Xing YangKey Laboratory of Biomedical Imaging Science and System, Chinese Academy of Sciences, State Key Laboratory of Biomedical Imaging Science and System, Guangdong Key Laboratory of Nanomedicine, CAS-HK Joint Lab for Biomaterials, Shenzhen Institutes of Advanced Technology, Shenzhen 518055, China.
Yehuda G AssarafThe Fred Wyszkowski Cancer Research Laboratory, Faculty of Biology, Technion-Israel Institute of Technology, Haifa 3200003, Israel.
Kai MiaoMoE Frontiers Science Center for Precision Oncology, Cancer Center, Faculty of Health Sciences, University of Macau, Taipa, Macau 999078, China.
Yue WangMoE Frontiers Science Center for Precision Oncology, Cancer Center, Faculty of Health Sciences, University of Macau, Taipa, Macau 999078, China.
Zhiwei ZhangFaculty of Pharmaceutical Sciences, Shenzhen University of Advanced Technology, Shenzhen 518107, China.
Duo ZhangFaculty of Pharmaceutical Sciences, Shenzhen University of Advanced Technology, Shenzhen 518107, China.
Yaping LiState Key Laboratory of Drug Research & Center of Pharmaceutics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Ping GongKey Laboratory of Biomedical Imaging Science and System, Chinese Academy of Sciences, State Key Laboratory of Biomedical Imaging Science and System, Guangdong Key Laboratory of Nanomedicine, CAS-HK Joint Lab for Biomaterials, Shenzhen Institutes of Advanced Technology, Shenzhen 518055, China.
Qi ZhaoMoE Frontiers Science Center for Precision Oncology, Cancer Center, Faculty of Health Sciences, University of Macau, Taipa, Macau 999078, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Repolarizing immunosuppressive M2-phenotype tumor-associated macrophages (TAMs) and blocking the CD47/SIRP

Indexed as

Apoptotic vesiclecGAS–STING pathwayImmunotherapyPhagocytosispH-responsive PEG coatingRepolarizationSIRPαTumor-associated macrophages

Identifiers

PMID42039278
PMCPMC13104663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.