Evidence map›Paper›PMID 42039264›Full record

ArticleActa pharmaceutica Sinica. B2026

Targeted intestinal barrier repair

Li Yu, He Zhang, Chengge Shi, Qiang Zhou, Jiayu Li, Bin Lu, Hongyang Lu, Ting Jin, Yinci Zhu, Tianci Zuo and 7 more

Abstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Dismantling the eDNA-mediated HBioactive materials · 2027
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  10. International journal of nanomedicine · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Li YuSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China.
He ZhangSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China.
Chengge ShiSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China.
Qiang ZhouDepartment of Neurosurgery, Shanghai Tenth People's Hospital of Tongji University, Shanghai 200072, China.
Jiayu LiSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China.
Bin LuSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China.
Hongyang LuSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China.
Ting JinSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China.
Yinci ZhuSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China.
Tianci ZuoSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China.
Mengzhu XuSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China.
Mingli SuSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China.
Yanmei ZhangSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China.
Quazi T H ShubhraInstitute of Chemistry, University of Silesia in Katowice, Katowice 40-006, Poland.
Xiaowen HuSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China.
Hui DengSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China.
Xiaojun CaiSchool and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal barrier disruption, driven by oxidative stress, ferroptosis, immune imbalance, and gut microbiota dysbiosis, plays a crucial role in inflammatory bowel disease (IBD) pathogenesis. Current treatments are often ineffective and cause side effects, emphasizing the need for novel therapies. Here, we have developed an engineered probiotic-derived outer membrane vesicle (OMV), GDO@CM, combining antioxidant gallic acid (GA) and anti-inflammatory H

Indexed as

FerroptosisGallic acidGut microbiotaH2S therapyImmunoregulationIntestinal epithelial barrierProbiotic-derived outer membrane vesiclesSingle-cell RNA sequencing

Identifiers

PMID42039264
PMCPMC13104641

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.