Evidence map›Paper›PMID 42039021›Full record

SynthesisFrontiers in psychology2026

Factors associated with sense of coherence in patients with malignant tumors: a systematic review and meta-analysis.

Wenqing Xu, Jiayao Wang, Tianxue Deng, Tao Xu, Wen Xiao, Jiansu Liao, Yuqing Zhou, Danfeng Gu

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenqing XuAffiliated Hospital of Jiangnan University, Wuxi, China.
Jiayao WangWuxi Medical College, Jiangnan University, Wuxi, China.
Tianxue DengWuxi Medical College, Jiangnan University, Wuxi, China.
Tao XuWuxi Medical College, Jiangnan University, Wuxi, China.
Wen XiaoWuxi Medical College, Jiangnan University, Wuxi, China.
Jiansu LiaoWuxi Medical College, Jiangnan University, Wuxi, China.
Yuqing ZhouAffiliated Hospital of Jiangnan University, Wuxi, China.
Danfeng GuAffiliated Hospital of Jiangnan University, Wuxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Sense of coherence (SOC) is a significant positive psychological resource that influences psychological outcomes and quality of life in patients with malignant tumors. This systematic review and meta-analysis aims to identify and synthesize factors associated with SOC in this population. Methods: A systematic search was carried out across 10 databases, from their inception to 12 October 2025, to identify studies exploring factors related to SOC in patients with malignant tumors. The Agency for Healthcare Research and Quality (AHRQ) Methodological Checklist and the Newcastle-Ottawa Scale (NOS) were used to evaluate the methodological quality of the included studies. Effect sizes were expressed as Pearson correlation coefficients ( Results: Thirty-six studies were finally included, involving 11,007 participants. The systematic review revealed many factors associated with SOC, including time since disease remission, absence of self-reported functional limitations and disability, use of complementary therapies, sexual function, number of combined chronic conditions, severity of somatic symptoms, cancer-related fatigue, coping strategies, self-esteem, the level of resourcefulness, self-advocacy, self-care ability, post-traumatic growth, aging adaptation, meaning in life, family function, partner's SOC, Type C personality, death anxiety, stigma, perceived stress, perceived hospital and surgery-related stress, psychological distress, unmet needs, self-perceived burden, social alienation, disease perception, and partner's depression level. The meta-analysis showed several factors significantly associated with SOC, including depression [ Conclusions: In this systematic review and meta-analysis, 35 factors were identified as related to SOC in patients with malignant tumors. Clinical practice should be guided by positive psychology and consider various relevant factors to comprehensively explore the developmental mechanisms of SOC in patients with malignant tumors, thereby building more targeted interventions to improve SOC. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251020931, identifier: CRD420251020931.

Indexed as

correlated factorsmalignant tumorsmeta-analysissense of coherencesystematic review

Identifiers

PMID42039021
PMCPMC13102640

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.