Evidence map›Paper›PMID 42039010›Full record

ReviewFrontiers in psychology2026

The 'hand-brain-emotion' axis: a theoretical model for handicraft art-based intervention in anxiety disorders through neuroplasticity and autonomic regulation.

Ruiqiao Guan, Wenxiao Wang, Jiaming Dai, Dengdeng Li

Abstract readReview
In one paragraph

Review in Frontiers in psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ruiqiao GuanDepartment of Chinese Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Wenxiao WangFaculty of Humanities and Arts, Macau University of Science and Technology, Taipa, Macao SAR, China.
Jiaming DaiFaculty of Humanities and Arts, Macau University of Science and Technology, Taipa, Macao SAR, China.
Dengdeng LiFaculty of Humanities and Arts, Macau University of Science and Technology, Taipa, Macao SAR, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review proposes a theoretical model, the hand-brain-emotion axis, which is based on the neuro psychological theory of how handicraft art activate specific brain regions to enhance neuroplasticity and emotional regulation. Anxiety disorders are common mental health disorders that have a profoundly impact on patients' quality of life. Current pharmacological treatments, while effective to some extent, are limited in efficacy and often accompanied by side effects. Against this backdrop, exploring non-pharmacological interventions has become crucial. Research has demonstrated that handicraft art activities can substantially attenuates anxiety levels and promote the secretion of neurotransmitters, thereby improving mental health. This review aims to provide a theoretical foundation for future clinical designs of diverse handicraft art programs to improve the emotional and cognitive functions of anxiety disorder patients. It also offers theoretical support for further exploring the dynamic effects of handicraft art activities on the brain using techniques such as neuroimaging and neuroelectrophysiology. The hand-brain-emotion axis theory presented in this review provides a solid theoretical basis for the application of handicraft art activities as a novel therapeutic approach for anxiety disorders. It is also expected to promote innovation and development in the fields of neuropsychological health and art therapy.

Indexed as

anxiety disorderhand-brain-emotion axishandicraftneuroplasticitynon-pharmaceutical treatment

Identifiers

PMID42039010
PMCPMC13102596

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.