ArticleGalen medical journal2025
Frequency of Dysnatremia in the First 24 Hours and Its Relationship with Mortality in Patients with Severe Brain Trauma : Dysnatremia and Head Trauma.
Article in Galen medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Background: Dysnatremia (hypernatremia and hyponatremia) is known to make hospitalized traumatic brain injury (TBI) patients vulnerable to morbidity and mortality. This investigation aimed at observing frequency of dysnatremia in the first 24 hours and its relationship with mortality in patients with traumatic brain injuries. Materials and Methods: Materials and Methods: This prospective descriptive-analytical study was conducted at Hashminejad Hospital in Mashhad from April 2023 to March 2024. The study sample included patients with severe traumatic brain injuries who referred to the emergency room of Hashminejad Hospital in Mashhad. Information about each patient, including age, sex, Glasgow coma score, blood pressure, plasma sodium, creatinine, serum sugar, calcium, potassium, blood urea nitrogen, and blood pressure at the beginning of admission. Mortality was checked up to 48 hours. Results: Results: A total of 81 patients with traumatic brain injuries, with an average age of 40.33 ± 19.47 years were included in the study; 85% were male and 15% were female. 32 patients (40%) died and the rest were discharged. Out of a total of 81 patients included in the study, 36 (44.5%) suffered from dysnatremia. 16 patients (19.8%) had hyponatremia and 20 (24.7%) had hypernatremia. The statistical results did not show any significant relationship between the sodium status of patients and their outcome. In the next step, statistical analysis showed that the patient's sodium level during hospitalization is not a predictor of mortality. Diastolic blood pressure and blood sugar in deceased patients were substantially higher than alive patients. The results showed that the only factor that could substantially predict the death of patients was blood sugar, so that every incremental rise in glucose level increased the chance of death by 1.018 times. Conclusion: Conclusion: The present study showed that although dysnatremia has no significant relationship with the outcome of brain trauma patients, it needs attention due to its high incidence rate (44.5%) in these patients. In addition, blood sugar was introduced as a factor that could predict the death of patients.
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