Evidence map›Paper›PMID 42038721›Full record

ArticleJournal of clinical and translational science2026

Precision risk assessment for pediatric hospitalization using address-level data in Cincinnati, Ohio.

Carson S Hartlage, Qing Duan, Erika Rasnick Manning, Judith W Dexheimer, Andrew F Beck, Cole Brokamp

Abstract read
In one paragraph

Article in Journal of clinical and translational science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Evaluating Linkage Approaches for Address-Level Socioenvironmental Exposure Assessment.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Carson S HartlageDepartment of Biostatistics, Health Informatics and Data Sciences, University of Cincinnati College of Medicine, Cincinnati, OH, USA.ORCID https://orcid.org/0000-0001-7875-8215
Qing DuanDivision of Biostatistics & Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Erika Rasnick ManningDivision of Biostatistics & Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Judith W DexheimerDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Andrew F BeckDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Cole BrokampDivision of Biostatistics & Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Funding

Enhancing the Sustainability and Impact of Geomarker Assessment Tools for ResearchR03ES037996 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI BROKAMP, COLE · 2025 to 2025
$482k
NIEHS NIH HHS R03 ES037996
6 · The paper itself

Abstract

Introduction: Persistent disparities in child health highlight the need for clinical and public health research approaches to identify and address risks with greater spatial precision. This study linked residence-and neighborhood-specific socio-environmental data to population-wide healthcare data to characterize pediatric hospitalization risk for every residential address in Cincinnati, Ohio. Methods: We linked hospitalization data (07/01/2016-06/30/2022) to parcel-level housing data from the Hamilton County Auditor and Cincinnati Department of Buildings & Inspections and street-range crime data from the Cincinnati Police Department. Addresses were localized to 2010 census tracts to join variables from the US Census American Community Survey and Eviction Lab. Generalized random forest models estimated address-level hospitalization risk and birth-adjusted hospitalization risk, accounting for child residency using vital birth records. Model performance was assessed based on varying diagnostic thresholds; fairness was evaluated by census block-level racial demographics. Results: We matched 81.5% of hospitalizations to residential addresses. Among 77,077 addresses, 7.4% had ≥1 hospitalization. Our model performed well (ROC-AUC: 0.98-0.99; PR-AUC: 0.65-0.72) in characterizing high-risk addresses, with housing violations, violent crime, and market total value among top features. The birth-adjusted model also showed high performance (ROC-AUC: 0.92-0.93; PR-AUC: 0.65-0.78) and moderate agreement with the hospitalization risk model ( Conclusions: Our results highlight the potential of address-level modeling and multiscale data integration to build on traditional area-level analyses and advance precision population health. Future directions include geographic expansion, stakeholder engagement, and patient-level validation. This work offers a scalable approach to precisely identifying pediatric health risks, supporting targeted clinical and policy interventions.

Indexed as

clinical informaticsdata aggregationenvironmental healthmachine learningpopulation health

Identifiers

PMID42038721
PMCPMC13107074

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.