Evidence map›Paper›PMID 42038703›Full record

ArticleBiodesign research2025

Identification and engineering of a UDP-rhamnosyltransferase from

Yuxin Yang, Haowen Wang, Ziya Wu, Xing Wang, Yuru Tong, Wei Huang, Xuan Liu, Huan Zhao, Juan Guo, Yating Hu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biodesign research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuxin YangSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
Haowen WangSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
Ziya WuSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
Xing WangSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
Yuru TongSchool of Pharmaceutical Science, Capital Medical University, Beijing, 100069, China.
Wei HuangSchool of Pharmaceutical Science, Hubei University of Chinese Medicine, Wuhan, 430060, China.
Xuan LiuSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
Huan ZhaoSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.
Juan GuoNational Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Yating HuNational Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China.
Xianan ZhangSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, 100069, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyphyllins, a class of isospirostan-type steroidal saponins, exhibit cytotoxicity against a wide range of cancer cells. Despite extensive research, the complete biosynthetic pathway of these compounds remains elusive. To investigate these pathways, various tissues from

Indexed as

BiosynthesisPolyphyllin ⅡProtein engineeringRhamnosyltransferaseTrillium tschonoskii

Identifiers

PMID42038703
PMCPMC13109326

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.