Evidence map›Paper›PMID 42038701›Full record

ArticleFrontiers in aging neuroscience2026

Risk score for futile recanalization: integrating cerebral circulation time and collateral cascade.

Xiaowen Song, Guo-Feng Zhao, Yong-Lin Qin, Zhi-Bin Bai, Jia-Jie Ji, Gang Deng

Abstract read
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In one paragraph

Article in Frontiers in aging neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaowen SongCenter of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.
Guo-Feng ZhaoCenter of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.
Yong-Lin QinCenter of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.
Zhi-Bin BaiCenter of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.
Jia-Jie JiCenter of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.
Gang DengCenter of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Impaired microvascular reperfusion despite successful recanalization may contribute to futile recanalization (FR) following thrombectomy. By combining cerebral circulation time (CCT) and cerebral collateral cascade (CCC) to evaluate hemodynamic and microcirculatory disturbances, we aim to develop and validate a new comprehensive prognostic model to predict FR after thrombectomy. Methods: This retrospective cohort study involved a thorough analysis of perfusion and collateral status (CCT and CCC) in consecutive acute ischemic stroke (AIS) patients presented with large vessel occlusion who underwent thrombectomy and achieved successful recanalization between January 2022 and December 2024. Independent predictors of FR were obtained from the least absolute shrinkage and selection operator regression and multivariable logistic regression. A nomogram model was constructed, and its discrimination and calibration were assessed. Results: This study included 182 patients, of whom 73 (40.11%) suffered from FR. Feature importance identified ischemic core volume (OR 1.01, 95% CI 1.00-1.03, Conclusion: The new prognostic model provides a valuable tool for predicting FR, thereby improving individualized stroke management.

Indexed as

acute ischemic strokecerebral circulation timecerebral collateral cascadefutile recanalizationmicrovascular reperfusion

Identifiers

PMID42038701
PMCPMC13106472

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.