ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2026
The changing epidemiology and long-term outcomes of patients with CRE infections.
Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Differential virulence potential of different clades of multidrug-resistantMicrobiology spectrum · 2026Article
- Differential virulence potential of different clades of multidrug-resistantmedRxiv : the preprint server for health sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The impact of organism species and underlying comorbidities on long-term clinical outcomes for patients with carbapenem-resistant Enterobacterales (CRE) infections is unknown. Methods: Patients with CRE-positive cultures from 2011 to 2019 were monitored for 1-year. Patients without signs of infection were categorized as colonization. Recurrent cases were defined as isolation of the same CRE species >90 days after the index case. Results: 720 patients met inclusion criteria and accounted for 749 index cases, which decreased over time. The median (range) age was 61 (20-97) years, 53% (397/749) were male, 20% (151/749) received solid organ transplant (SOT), and 44% resided in the ICU at the time of CRE isolation. The colonization rate was 34% (257/749). Pneumonia and bacteremia represented the most common infection types accounting for 25% (185/749) and 13% (95/749) of all cases, respectively. Conclusion: CRE are increasingly diverse and associated with significant morbidity and healthcare utilization across varying patient groups. Long-term survival of patients infected with CRE has improved over time while overall incidence of CRE has decreased.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.