Evidence map›Paper›PMID 42038547›Full record

Trial reportOpen forum infectious diseases2026

A Randomized Controlled Trial of the My Personal Health Guide Mobile Phone App on ART Adherence Among Young African American Men Who Have Sex With Men Living With HIV in the United States.

Mark S Dworkin, Kara Herrera, Sierra Upton, Jeb Jones, Li Liu, Ruiqi Ren, Casey M Luc, Paul Burns, Antonio Jimenez, Meaghan Woody and 2 more

Abstract readClinical Trial
In one paragraph

Trial report in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mark S DworkinSchool of Public Health, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0003-0974-8368
Kara HerreraSchool of Public Health, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0009-0008-4424-6359
Sierra UptonSchool of Public Health, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0009-0006-5733-5751
Jeb JonesRollins School of Public Health, Emory University, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0001-9165-1658
Li LiuSchool of Public Health, University of Illinois at Chicago, Chicago, Illinois, USA.
Ruiqi RenSchool of Public Health, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0009-0000-0486-7128
Casey M LucSchool of Public Health, University of Illinois at Chicago, Chicago, Illinois, USA.
Paul BurnsSchool of Population Health, University of Mississippi Medical Center, Jackson, Mississippi, USA.ORCID https://orcid.org/0000-0001-9882-649X
Antonio JimenezSchool of Public Health, University of Illinois at Chicago, Chicago, Illinois, USA.
Meaghan WoodyRollins School of Public Health, Emory University, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0001-5858-3243
Robert GarofaloAdolescent Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0001-9513-9416
Sangyoon LeeDepartment of Computer Science, Connecticut College, New London, Connecticut, USA.ORCID https://orcid.org/0000-0002-0749-7641

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We created My Personal Health Guide, a relational agent-based mobile health app to improve antiretroviral therapy (ART) adherence among young African American men who have sex with men (AAMSM), a priority population for developing treatment-as-prevention interventions. We assessed the efficacy of My Personal Health Guide on improving ART adherence among young AAMSM with HIV over 6 months. Methods: We implemented a randomized controlled trial among young AAMSM (18-34 years) with nonoptimal ART adherence throughout the United States. Participants were randomized to My Personal Health Guide or a control arm. ART adherence was assessed with Wilson's 3-item self-reported adherence measurement and dichotomized at ≥80%. Generalized estimating equations were employed to evaluate the effect of My Personal Health Guide over time, with Results: A significant group effect ( Conclusions: This randomized controlled trial demonstrated statistically significant efficacy of the My Personal Health Guide app in improving ART adherence among young AAMSM. As hypothesized, a >10% effect for improved ART adherence was observed at 6-month follow-up among those randomized to the My Personal Health Guide app. These findings provide evidence of efficacy out to 6 months of My Personal Health Guide use to improve ART adherence among young AAMSM.

Indexed as

adherenceantiretroviral therapyHIVmHealthrelational agent

Identifiers

PMID42038547
PMCPMC13107962

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.