Evidence map›Paper›PMID 42038533›Full record

ArticleSmall structures2025

A Machine Learning Approach to Quantitative Analysis of Enamel Microstructure from Scanning Electron Microscopy Images.

Carli Marsico, Cameron Renteria, Jack R Grimm, Juliana Fernandez-Arteaga, Donna Guillen, Dwayne Arola

Abstract read
In one paragraph

Article in Small structures, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carli MarsicoDepartment of Materials Science and Engineering, University of Washington, Box 352120, Seattle 98195, WA, USA.
Cameron RenteriaDepartment of Materials Science and Engineering, University of Washington, Box 352120, Seattle 98195, WA, USA.
Jack R GrimmDepartment of Materials Science and Engineering, University of Washington, Box 352120, Seattle 98195, WA, USA.
Juliana Fernandez-ArteagaScience and Humanities Faculty, Institución Universitaria Digital de Antioquia, Medellín 050010, Colombia.
Donna GuillenMaterials Science and Engineering Department, Idaho National Laboratory, Idaho Falls 98195, ID, USA.
Dwayne ArolaDepartment of Materials Science and Engineering, University of Washington, Box 352120, Seattle 98195, WA, USA.

Funding

Comprehensive Training in Inter-Disciplinary Oral Health ResearchT90DE021984 · NIDCR · UNIVERSITY OF WASHINGTON · PI Robert Aaron Cornell · 2012 to 2026
$7.9M
NIDCR NIH HHS T90 DE021984
6 · The paper itself

Abstract

Dental enamel, the outermost tissue of mammalian teeth, must withstand a lifetime of wear and cyclic contact. To meet this demand, enamel possesses a combination of high hardness and resistance to fracture, properties that are typically mutually exclusive. The impressive damage tolerance has been attributed largely to decussation of the enamel rods, the principal unit of its microstructure. As such, enamel is inspiring the design of next-generation structural materials. However, quantitative descriptions of the decussated enamel rod microstructure remain limited due to challenges encountered in applying computed tomography and in acquiring quality images appropriate for traditional digital processing methods. Here, a machine learning segmentation method is applied to images of the enamel obtained using scanning electron microscopy to support quantitative analysis of the microstructure. A pretrained convolutional neural network is used to expand the input training image dataset to allow the training of a random forest classifier, which ultimately segments the image with a very small training set (

Indexed as

bioinspirationsenamelimage analysesmachine learningmachine visionsscanning electron microscopies

Identifiers

PMID42038533
PMCPMC13105305

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.