ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2026
The Association of the Timing of Physical Activity with Cardiometabolic Health in Diabetes: An IMI2 SOPHIA Study.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study aimed to investigate the association of timing of the most active five hours (M5 time) with markers of cardiometabolic health in people with type 1 diabetes (T1D) and type 2 diabetes (T2D). Patients and Methods: People with T1D or T2D were invited to participate in the study. Physical activity was measured over a 7-day period with a wrist worn accelerometer. The M5time (as a linear and circular (sin-cos) variable) and the amount of activity in these five hours (M5value) were calculated, and associations with glycaemic control, blood lipids and body composition were examined using multiple linear regression, with multiple testing controlled using false discovery rate (FDR) correction. Results: A total of 891 people with T1D and 1381 people with T2D were included. In people with T1D, M5time (linear) was associated with waist circumference after full adjustment (model 3) (B = -0.32, SE = 0.15, FRD p = 0.047). Similarly, in people with T1D M5 time (circular) was also significantly associated with BMI (p = 0.004) and waist circumference (p = 0.001), with amplitudes of BMI: 1.32 kg/m2 and Waist: 4.28 cm, and phases of BMI: 12:51h and Waist: 13:06h. In people with T2D, M5 time was not associated with any cardiometabolic markers after FDR correction in any adjusted models. Conclusion: In people with T1D, the time of day at which people were most active was associated with some cardiometabolic markers. However, in people with T2D, there was no association with any cardiometabolic markers. Overall, our data indicates little effect of time of and physical activity at any time of day should be promoted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.