Evidence map›Paper›PMID 42038486›Full record

ArticleACS central science2026

Detecting Bacteria in Their Mammalian Hosts Using Metabolism-Targeted [

Marina López-Álvarez, Sang Hee Lee, Anju Wadhwa, Mohammad Yaqoob Bhat, Tyler S Simmons, Jung Min Kim, Anil P Bidkar, Spenser R Simpson, Shari Dhaene, Jeffrey D Steinberg and 11 more

Erratum issuedAbstract read
In one paragraph

Article in ACS central science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Expanding theACS central science · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Marina López-ÁlvarezDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.
Sang Hee LeeDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.ORCID https://orcid.org/0000-0001-8578-9968
Anju WadhwaDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.ORCID https://orcid.org/0009-0006-0826-8134
Mohammad Yaqoob BhatDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.ORCID https://orcid.org/0000-0002-0888-5603
Tyler S SimmonsDepartment of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Jung Min KimDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.ORCID https://orcid.org/0009-0003-9492-510X
Anil P BidkarDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.
Spenser R SimpsonDepartment of Radiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.ORCID https://orcid.org/0000-0001-9731-8354
Shari DhaeneDepartment of Biotechnology, Centre for Synthetic Biology, Ghent University, Gent B-9000, Belgium.ORCID https://orcid.org/0000-0003-0887-7651
Jeffrey D SteinbergCenter for In Vivo Imaging and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Joseph BlechaDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.
Robert R FlavellDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.ORCID https://orcid.org/0000-0002-8694-1199
Marshall D McCueSable Systems International, Las Vegas, Nevada 89032, United States.
Amanda M GreenDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.ORCID https://orcid.org/0009-0006-2250-2687
Renuka SriramDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.ORCID https://orcid.org/0000-0003-3505-2479
Tom DesmetDepartment of Biotechnology, Centre for Synthetic Biology, Ghent University, Gent B-9000, Belgium.ORCID https://orcid.org/0000-0002-5788-3022
Joanne EngelDepartment of Medicine, University of California, San Francisco, San Francisco, California 94158, United States.
Jason W RoschDepartment of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Michael A OhligerDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.
Kiel D NeumannDepartment of Radiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.ORCID https://orcid.org/0000-0001-9093-3522
David M WilsonDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.ORCID https://orcid.org/0000-0002-1095-046X

Funding

New radiotracer development to study immune cell mobilization of granzyme proteolytic activityR01AI161027 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CRAIK, CHARLES SCOTT, EVANS, MICHAEL JOHN · 2021 to 2024
$2.8M
Sensing living P. aeruginosa using D-alanine derived radiotracersR01EB030897 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ENGEL, JOANNE N., OHLIGER, MICHAEL · 2021 to 2024
$2.7M
Chemoenzymatic radiosyntheses of [18F]FDG-derived oligosaccharides for S. aureus detectionR01AI181378 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Michael Ohliger, David M Wilson · 2024 to 2026
$2.3M
Novel imaging agents of oxidative stress in the pathophysiology of the central nervous systemR01EB028338 · NIBIB · UNIVERSITY OF VIRGINIA · PI NEUMANN, KIEL · 2020 to 2020
$2.1M
[18F]fluoromannitol: A novel imaging agent to delineate osteomyelitis in sickle cell diseaseR01AI192221 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Amanda Marie Green, Kiel Neumann · 2025 to 2026
$1.8M
Novel pro-drug imaging agents to detect neuroinflammation in Alzheimer's DiseaseR01AG093113 · NIA · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Chia-Yi Kuan, Kiel Neumann · 2026 to 2026
$759k
Imaging bacterial infection using deuterium-enriched sugar alcohols.R21AI164684 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WILSON, DAVID M · 2021 to 2022
$444k
NIAID NIH HHS R01 AI161027NIAID NIH HHS R01 AI181378NIAID NIH HHS R01 AI192221NIAID NIH HHS R21 AI164684NIA NIH HHS R01 AG093113NIBIB NIH HHS R01 EB028338NIBIB NIH HHS R01 EB030897
6 · The paper itself

Abstract

Infectious diseases are a major cause of morbidity and mortality worldwide. With the increasing frequency of antibiotic resistance, efficient and noninvasive diagnostic methods are more important than ever. In this report, we interrogate the use of several intravenously administered, bacteria-specific,

Identifiers

PMID42038486
PMCPMC13107215

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.