Evidence map›Paper›PMID 42038417›Full record

ArticleArXiv2026

Universal principles of cell population growth follow from local contact inhibition.

Gregory J Kimmel, Sadegh Marzban, Mehdi Damaghi, Arne Traulsen, Alexander R A Anderson, Jeffrey West, Philipp M Altrock

Abstract readPreprint
In one paragraph

Article in ArXiv, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Gregory J KimmelDepartment of Integrated Mathematical Oncology, Moffitt Cancer Center, Tampa, FL, USA.
Sadegh MarzbanDepartment of Integrated Mathematical Oncology, Moffitt Cancer Center, Tampa, FL, USA.
Mehdi DamaghiStony Brook Cancer Center, Stony Brook School of Medicine, Stony Brook University, Stony Brook, NY, USA.
Arne TraulsenDepartment of Theoretical Biology, Max Planck Institute for Evolutionary Biology, Ploen, Germany.
Alexander R A AndersonDepartment of Integrated Mathematical Oncology, Moffitt Cancer Center, Tampa, FL, USA.
Jeffrey WestDepartment of Integrated Mathematical Oncology, Moffitt Cancer Center, Tampa, FL, USA.
Philipp M AltrockDepartment of Theoretical Biology, Max Planck Institute for Evolutionary Biology, Ploen, Germany.

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI John L. Cleveland · 1998 to 2026
$93.5M
"Research Supplement to Promote Diversity in Health-Related Research", as part of Moffitt PS-OC, "Cancer as a Complex adaptive System"U54CA193489 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI ANDERSON, ALEXANDER ROBERTSON ALLAN, GATENBY, ROBERT A · 2015 to 2020
$12.5M
NCI NIH HHS P30 CA076292NCI NIH HHS U54 CA193489
6 · The paper itself

Abstract

Cancer cell populations often exhibit remarkably similar growth laws despite their heterogeneity. Explanations of universal cell population growth remain partly unresolved to this day. Here, we present a growth-law unification by investigating the connection between microscopic assumptions and the expected contact inhibition, which leads to five classical tumor growth laws: exponential, radial growth, fractal growth, generalized logistic, and Gompertzian growth. All five can be seen as manifestations of a single microscopic model. Agent-based simulations substantiate our theory, and we can explain differences in growth curves in experimental data from

Indexed as

cancer growth curvescell motilitycontact inhibitionPopulation growth

Identifiers

PMID42038417
PMCPMC13105202

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.