Evidence map›Paper›PMID 42038374›Full record

ArticleFrontiers in oncology2026

Case Report: Giant undifferentiated pleomorphic sarcoma of the breast combined with contralateral high-grade intraductal carcinoma.

Zhikun Zhao, Lei Cao, Shengju Xu, Fan Yang, Shang Gao, Chuanxin Ren, Xingchao Xu, Xiangqi Li

Abstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhikun Zhao *Department of General Surgery, Second Affiliated Hospital of Shandong First Medical University, Tai'an, Shandong, China.
Lei Cao *Department of Breast Surgery, The Affiliated Taian City Central Hospital of Qingdao University, Tai'an, Shandong, China.
Shengju XuDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Shandong First Medical University, Tai'an, Shandong, China.
Fan YangDepartment of Pathology, The Second Affiliated Hospital of Shandong First Medical University, Tai'an, Shandong, China.
Shang GaoDepartment of Breast Surgery, The Second Affiliated Hospital of Shandong First Medical University, Shandong, Tai'an, China.
Chuanxin RenDepartment of Breast Surgery, The Second Affiliated Hospital of Shandong First Medical University, Shandong, Tai'an, China.
Xingchao XuDepartment of Breast Surgery, The Second Affiliated Hospital of Shandong First Medical University, Shandong, Tai'an, China.
Xiangqi LiDepartment of Breast Surgery, The Second Affiliated Hospital of Shandong First Medical University, Shandong, Tai'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article reports an exceptionally rare case of a 43-year-old female presenting with concurrent giant pleomorphic undifferentiated sarcoma and high-grade intraductal carcinoma of the contralateral breast. The tumor, remarkably large and comparable in size to a basketball, presented significant diagnostic and therapeutic challenges. Following a multidisciplinary consultation, the patient underwent a comprehensive treatment regimen, which included left mastectomy, modified radical mastectomy, vacuum-assisted closure (VSD) negative pressure drainage, radiotherapy, and endocrine therapy for the high-grade intraductal carcinoma. Post-treatment follow-up over a period of 2 to 5 years revealed a satisfactory recovery with no evidence of recurrence or metastasis. This case underscores the critical role of a multidisciplinary approach in managing rare and complex breast malignancies and highlights the potential for favorable outcomes even in cases involving exceptionally large tumors.

Indexed as

breast cancercase reporthigh-grade intraductal carcinomamultidisciplinary treatmentundifferentiated pleomorphic sarcoma

Identifiers

PMID42038374
PMCPMC13105915

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.