ArticleRSC advances2026
Copper-catalyzed one-pot synthesis of isoquinolines
Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
2 authors.
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Abstract
A copper-catalyzed multicomponent protocol is described for the synthesis of structurally diverse isoquinolines from readily available phenylacetaldehyde derivatives, benzaldehydes, and ammonia. A commercially available 4 M solution of ammonia in methanol serves as a practical and comparatively benign nitrogen source, avoiding the use of prefunctionalized amine substrates. The transformation proceeds at room temperature
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Registered trials
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