Evidence map›Paper›PMID 42038166›Full record

ArticleClinical kidney journal2026

Renal allograft malakoplakia mimicking malignancy: the value of combined morphological and functional imaging.

Nerea Fordel, Valerie Neirynck, Céline Seghers, Raf Sciot, Thomas Tousseyn, Hanna Verlinden, Claire Vanderpluijm, Niels Schepens, Dirk Kuypers, Papay Jallah and 2 more

Abstract read
In one paragraph

Article in Clinical kidney journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nerea FordelDepartment of Nephrology, Sint Lucas Ghent General Hospital, Ghent, Belgium.ORCID https://orcid.org/0009-0001-5532-6994
Valerie NeirynckDepartment of Nephrology, Sint Lucas Ghent General Hospital, Ghent, Belgium.
Céline SeghersDepartment of Nephrology, Sint Lucas Ghent General Hospital, Ghent, Belgium.ORCID https://orcid.org/0000-0002-8060-5063
Raf SciotDepartment of Pathology, University Hospitals Leuven, University of Leuven, Leuven, Belgium.
Thomas TousseynDepartment of Pathology, University Hospitals Leuven, University of Leuven, Leuven, Belgium.
Hanna VerlindenDepartment of Nephrology and Renal Transplantation, University Hospitals Leuven, University of Leuven, Leuven, Belgium.
Claire VanderpluijmDepartment of Nephrology and Renal Transplantation, University Hospitals Leuven, University of Leuven, Leuven, Belgium.
Niels SchepensDepartment of Nephrology and Renal Transplantation, University Hospitals Leuven, University of Leuven, Leuven, Belgium.
Dirk KuypersDepartment of Nephrology and Renal Transplantation, University Hospitals Leuven, University of Leuven, Leuven, Belgium.
Papay JallahDepartment of Nephrology and Renal Transplantation, University Hospitals Leuven, University of Leuven, Leuven, Belgium.
Helena van den HoutDepartment of General Internal Medicine, University Hospitals Leuven, University of Leuven, Leuven, Belgium.
Maarten NaesensDepartment of Nephrology and Renal Transplantation, University Hospitals Leuven, University of Leuven, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Malakoplakia is a rare, chronic granulomatous inflammatory condition that primarily affects the genitourinary tract, albeit rarely renal allografts. This article highlights the clinical presentation and radiological features of renal allograft malakoplakia and aims to identify knowledge gaps by a pooled analysis of case reports. Methods: This study contains a detailed case report focusing on the presentation and radiological evolution of renal allograft malakoplakia, followed by a pooled analysis of 38 histologically confirmed cases, extracted from 34 publications. Descriptive statistics were applied. Results: Malakoplakia of the renal allograft generally affects female (79%), middle-aged (mean 48 years) kidney transplant recipients in the first 2 years after transplantation (68.4%, mean 19 months), with a history of recurrent Conclusions: Renal allograft malakoplakia is a rare but serious condition that in worst cases leads to graft loss and death. Prospective studies are needed to establish standardized diagnostic and therapeutic approaches, including the potential role of FDG-PET-CT in monitoring treatment response.

Indexed as

allograft malakoplakiamalakoplakiarenal transplanttransplant malakoplakia

Identifiers

PMID42038166
PMCPMC13103660

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.