Evidence map›Paper›PMID 42038022›Full record

ArticleJournal of Cancer2026

Association between Oxidative Balance Score and Colorectal Cancer: Insights from NHANES 1999-2018.

Danjing Chen, Bingqin Xie, Hua Fang, Huajing Chang, Wenxin Qiu, Jiangwang Fang, Yunli Wu, Xian-E Peng

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In one paragraph

Article in Journal of Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Danjing ChenDepartment of Epidemiology and Health Statistics, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, 350108, China.
Bingqin XieDepartment of Epidemiology and Health Statistics, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, 350108, China.
Hua FangDepartment of Epidemiology and Health Statistics, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, 350108, China.
Huajing ChangDepartment of Epidemiology and Health Statistics, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, 350108, China.
Wenxin QiuDepartment of Epidemiology and Health Statistics, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, 350108, China.
Jiangwang FangDepartment of Epidemiology and Health Statistics, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, 350108, China.
Yunli WuKey Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, School of Basic Medical Sciences, Fujian Medical University, Fuzhou 350108, China.
Xian-E PengDepartment of Epidemiology and Health Statistics, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, 350108, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Previous studies have indicated an association between high antioxidant exposure and colorectal cancer (CRC) risk in elderly populations. However, the relationship between the oxidative balance score (OBS) and CRC risk in the general population remains unclear. Objective: In this study, we used the OBS, which is based on dietary and lifestyle factors, to assess the oxidative stress (OS) status of individuals and to explore the association between OBS and CRC risk in American adults. Methods: Overall, 44,482 participants from the National Health and Nutrition Examination Survey (NHANES 1999-2018) were included in the cross-sectional study, of whom 340 had CRC. OBS, which consists of 20 dietary and lifestyle factors, was the exposure variable. Weighted multivariate logistic regression, subgroup analysis, and restricted cubic spline curves were used to assess the association between OBS and CRC. Sensitivity analyses were conducted to evaluate the robustness of the results. Results: Multiple logistic regression showed that the CRC risk decreased by 2.0% for each OBS unit added ( Conclusion: Higher OBS and dietary OBS were associated with CRC. A healthy lifestyle and antioxidant-rich diet may be useful for preventing CRC.

Indexed as

colorectal cancercross-sectional studyoxidative balance scoreoxidative stressrisk

Identifiers

PMID42038022
PMCPMC13105159

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.