Evidence map›Paper›PMID 42037989›Full record

ArticleIEEE sensors journal2026

Fiber-Tip Surface-Micromachined Optical Ultrasound Transducer (SMOUT) Probe for Acoustic Detection Induced by Ultrahigh Dose Rate (UHDR) Electron Beam.

Cheng Fang, Borui Li, Dale W Litzenberg, Issam El Naqa, Wei Zhang, Xueding Wang, Jun Zou

Abstract read
In one paragraph

Article in IEEE sensors journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cheng FangDepartment of Electrical and Computer Engineering, Texas A&M University, College Station, TX 77843, USA.
Borui LiDepartment of Electrical and Computer Engineering, Texas A&M University, College Station, TX 77843, USA.
Dale W LitzenbergDepartment of Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI 48109-0674, USA.
Issam El NaqaDepartment of Machine Learning and Department of Radiation Oncology, Moffitt Cancer Center, Tampa, FL 33612.
Wei ZhangDepartment of Biomedical Engineering, University of Michigan Medical School, Ann Arbor, MI 48109-0674, USA.
Xueding WangDepartment of Biomedical Engineering, University of Michigan Medical School, Ann Arbor, MI 48109-0674, USA.
Jun ZouDepartment of Electrical and Computer Engineering, Texas A&M University, College Station, TX 77843, USA.

Funding

An Ionizing Radiation Acoustics Imaging (iRAI) Approach for guided Flash RadiotherapyR01CA266803 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI BORTFELD, THOMAS R., EL NAQA, ISSAM M. · 2022 to 2025
$3.3M
A novel transducer clip-on device to enable accessible and functional 3D ultrasound imagingR01EB031040 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SONG, PENGFEI · 2022 to 2025
$2.1M
NCI NIH HHS R01 CA266803NIBIB NIH HHS R01 EB031040
6 · The paper itself

Abstract

Online dose mapping is essential for safe and accurate beam delivery in FLASH radiation therapy (RT). While ionizing radiation acoustic imaging (iRAI) enables real-time, deep tissue dose measurement and beam localization for RT, previous piezoelectric acoustic sensors have suffered from electronic noise and neutron damage from ultra-high dose rate radiation (UHDR) beam. Described here is an innovative single-element full-optical surface-micromachined optical ultrasound transducer (SMOUT) mounted on an optical fiber tip to detect acoustic waves induced by UHDR beam. The design and fabrication of the fiber-tip SMOUT probe (diameter = 400 μm) have been demonstrated, and its optical and acoustic characteristics, as well as transmittance to the FLASH electron beam and imaging capability have been characterized. Experimental results show that the fiber-tip SMOUT probe has optical resonance wavelength (ORW) ~ 773 nm, acoustic central frequency ~ 300 kHz and -6 dB acoustic bandwidth ~ 160 kHz, and dose rate independent single pulse noise equivalent dose ~ 5.19 cGy. More importantly, the fiber-tip SMOUT probe exhibits negligible disturbance to FLASH irradiation. After 1-D scanning the fiber-tip SMOUT probe, the 2-D dose distribution of the FLASH electron beam can be mapped with high consistency. These findings highlight the potential of SMOUT based iRAI for mapping the dose distribution under UHDR beam, which is an important step toward practical implementation of iRAI-based online dosimetry in FLASH RT.

Indexed as

dosimetryfiber-tip probeFLASH radiation therapyionizing radiation acoustic imaging (iRAI)single-element surface-micromachined optical ultrasound transducer (SMOUT)Ultra-high dose rate (UHDR)

Identifiers

PMID42037989
PMCPMC13105313

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.